Interrogating the Small Intestine Tuft Cell–ILC2 Circuit Using In Vivo Manipulations

Interrogating the Small Intestine Tuft Cell–ILC2 Circuit Using In Vivo Manipulations

Recent findings position tuft cells as key mediators of intestinal immunity through their production of the cytokine interleukin (IL)-25 and activation of group 2 innate lymphoid cells (ILC2s). Though tuft cells are found in numerous epithelial tissues, their phenotype and function have been best ch...

Full description

Bibliographic Details
Main Authors: Cortez, V.S (Author), Feng, X. (Author), Locksley, R.M (Author), O'Leary, C.E (Author), Schneider, C. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
adult
animal
animal cell
animal experiment
animal model
animal tissue
Animals
Article
cell function
controlled study
drinking water
ex vivo study
female
flow cytometry
gain of function mutation
group 2 innate lymphoid cells (ILC2s)
helminth infection
IL-25
Immunity, Innate
in vivo study
innate immunity
intestine cell
Intestine, Small
loss of function mutation
lymphocyte
Lymphocytes
lymphoid cell
male
mouse
Nippostrongylus
Nippostrongylus brasiliensis
nonhuman
parasites
phenotype
priority journal
recombinant cytokine
recombinant interleukin 25
signal transduction
small intestinal tuft cell
small intestine
strongyle infection
succinate
succinic acid
trichomoniasis
Tritrichomonas
Tritrichomonas spp
tuft cells
type 2 cytokine signaling
type 2 immunity
unclassified drug
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items