Down-regulated IL36RN expression based on peripheral blood mononuclear cells and plasma of periodontitis patients and its clinical significance

Background: The role of IL-36 receptor antagonist (IL36RN), a mutated gene expression of IL-36 in periodontitis patients with peripheral blood mononuclear cells (PBMC) and plasma remains to be undetermined. Materials and methods: Our study discovered the IL36RN expression through GEO public database...

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Bibliographic Details
Main Authors:	Liang, Y. (Author), Zhou, Y. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult Adult Article biological marker Biomarkers blood blood sampling case control study Case-Control Studies controlled study cytokine cytokines Cytokines diagnostic test accuracy study disease severity down regulation Down-Regulation enzyme linked immunosorbent assay female Female genetics human Humans IL36RN IL36RN protein, human interleukin 1beta interleukin 36 receptor antagonist interleukin 6 interleukin derivative Interleukins Leukocytes, Mononuclear major clinical study male Male metabolism middle aged Middle Aged mononuclear cell pathogenesis PBMC periodontitis Periodontitis peripheral blood mononuclear cell plasma protein analysis protein blood level protein expression receiver operating characteristic Retrospective Studies retrospective study reverse transcription polymerase chain reaction RNA isolation tumor necrosis factor unclassified drug
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Down-regulated IL36RN expression based on peripheral blood mononuclear cells and plasma of periodontitis patients and its clinical significance

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