Hyperleucocytosis grading score and NPM1 gene mutation among patients with acute myeloid leukemia: Malaysian experience

Hyperleucocytosis grading score and NPM1 gene mutation among patients with acute myeloid leukemia: Malaysian experience

This is the first study evaluating the frequencies of nucleophosmin (NPM1) gene mutation according to the hyperleukocytosis (HL) grading score. The current two cut off values of this score in acute myeloid leukaemia (AML) patients are [1] those with 50–100 × 109/L and [2] those with ≥ 100 × 109/L to...

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Bibliographic Details
Main Authors: Abdullah, U.Y.H (Author), Alwi, Z.B (Author), Azzubaidi, M.S (Author), Fakhruzzaman, M.N (Author), Ibrahim, H.M (Author), Jassim, H.M (Author), Johan, M.F (Author), Osman, R. (Author), Salleh, M.Z (Author), Simbak, N. (Author), Teh, L.K (Author), Yunus, N.M (Author)
Format: Article
Language:English
Published: Springer, 2020
Subjects:
Acute myeloid leukaemia
acute myeloid leukemia
Article
bioinformatics
blood cell count
bone marrow biopsy
cancer grading
controlled study
cross-sectional study
DNA sequencing
erythrocyte count
gene mutation
genomic DNA
Grading score
hemoglobin
human
human cell
human tissue
Hyperleucocytosis
hyperleukocytosis
immunophenotyping
karyotype
leukocyte count
leukocytosis
major clinical study
Malaysia
mean corpuscular hemoglobin
mean corpuscular volume
Mutation
NPM1 gene
nucleophosmin
platelet count
polymerase chain reaction
priority journal
scoring system
sequence alignment
sequence analysis
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