Global chromosome topology and the two-component systems in concerted manner regulate transcription in streptomyces

Global chromosome topology and the two-component systems in concerted manner regulate transcription in streptomyces

Bacterial gene expression is controlled at multiple levels, with chromosome supercoiling being one of the most global regulators. Global DNA supercoiling is maintained by the orchestrated action of topoisomerases. In Streptomyces, mycelial soil bacteria with a complex life cycle, topoisomerase I dep...

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Bibliographic Details
Main Authors: Bartynska, M. (Author), Biały, S. (Author), Elliot, M.A (Author), Gierlikowska, A. (Author), Gongerowska-Jac, M. (Author), Jakimowicz, D. (Author), Mikołajczyk, J. (Author), Szafran, M.J (Author), Szymczak, J. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
agar gel electrophoresis
Article
chromosome
controlled study
DNA replication origin
DNA supercoiling
DNA topoisomerase
drug manufacture
gene
gene activity
gene control
gene expression
gene induction
genetic background
genetic transcription
genotype
nonhuman
phase contrast microscopy
phenotype
RNA sequencing
room temperature
soil microflora
sporogenesis
Sporulation
Streptomyces
Streptomyces coelicolor
supercoiling hypersensitive cluster gene
Topoisomerases
Transcription factors
transcription regulation
Transcriptional regulation
transcriptomics
transposon
transposon mutagenesis
Two-component system
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