Protective effects of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone chalcone in indomethacin-induced gastric erosive damage in rats

Protective effects of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone chalcone in indomethacin-induced gastric erosive damage in rats

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Background: Non-steroidal anti-inflammatory drugs (NSAIDs) can result in peptic ulcer disease (PUD) which is a common condition worldwide. The aim of this study was to evaluate the antiulcer properties of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone) (HPTP) chalcone in rats using indomethacin as ulcero...

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Bibliographic Details
Main Authors: Abdulla, M.A (Author), Amin, Z.A (Author), Darvish, P.H (Author), Dhiyaaldeen, S.M (Author), Jamil, M.M (Author), Mustafa, I.F (Author), Rouhollahi, E. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd. 2014
Subjects:
1-(4-hydroxyphenyl)-3-m-tolylpropenone
animal
Animals
Anti-Inflammatory Agents, Non-Steroidal
Antioxidant
antiulcer agent
Anti-Ulcer Agents
blood
Chalcone
chalcone derivative
Chalcones
chemically induced
drug effects
Endogenous enzymes
female
Female
Gastric Mucosa
Histology
Immunohistochemistry
indometacin
Indomethacin
kidney
Kidney
lipid
Lipids
liver
Liver
male
Male
nonsteroid antiinflammatory agent
peptic ulcer
Peptic ulcer
Peptic Ulcer
rat
Rats
Rats, Sprague-Dawley
Sprague Dawley rat
stomach mucosa
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