Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse

Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse

At synapses, the pre- and postsynaptic cells get so close that currents entering the cleft do not flow exclusively along its conductance, gcl. A prominent example is found in the calyx of Held synapse in the medial nucleus of the trapezoid body (MNTB), where the presynaptic action potential can be r...

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Bibliographic Details
Main Authors: Borst, G.J.G (Author), Sierksma, M.C (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
action potential
Action Potentials
animal
Animals
Article
biological model
biology
C57BL mouse
calcium channel
Calcium Channels
calcium current
Computational Biology
conceptual framework
fenestration
geometry
Mice
Mice, Inbred C57BL
Models, Neurological
mouse
nerve ending
physiology
prediction
presynaptic potential
Presynaptic Terminals
synapse
Synapses
trapezoid body
Trapezoid Body
voltage clamp technique
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