Diversified lineages and drug-resistance profiles of clinical isolates of Mycobacterium tuberculosis complex in Malaysia

Diversified lineages and drug-resistance profiles of clinical isolates of Mycobacterium tuberculosis complex in Malaysia

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Background: Tuberculosis (TB) is still a major health problem in Malaysia with thousands of cases reported yearly. This is further burdened with the emergence of multidrug-resistant TB (MDR-TB). Whole-genome sequencing (WGS) provides high-resolution molecular epidemiological data for the accurate de...

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Bibliographic Details
Main Authors: Abidin, N.Z (Author), Aziz, Z.A (Author), Farida Zuraina, M.Y (Author), Hani, M.H (Author), Hisyam, M.J (Author), Lim, W.F (Author), Noorizhab Fakhruzzaman, M.N (Author), Noorliza, M.N (Author), Norazmi, M.N (Author), Norhayati, R. (Author), Richard, J.J (Author), Teh, L.K (Author), Zaki, M.S (Author), Zamzurina, A.B (Author)
Format: Article
Language:English
Published: NLM (Medline) 2019
Subjects:
Antitubercular Agents
bacterial genome
drug effect
Drug Resistance, Multiple, Bacterial
genetics
Genome, Bacterial
genotype
Genotype
human
Humans
Malaysia
microbial sensitivity test
Microbial Sensitivity Tests
microbiology
multidrug resistance
Multidrug resistance
multidrug resistant tuberculosis
mutation
Mutation
Mycobacterium tuberculosis
next-generation sequencing-based drug susceptibility testing screening
phenotypic drug susceptibility testing screening
Polymorphism, Single Nucleotide
single nucleotide polymorphism
tuberculosis
Tuberculosis
Tuberculosis, Multidrug-Resistant
tuberculostatic agent
whole genome sequencing
Whole Genome Sequencing
whole-genome sequence
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