Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma
The pathogenesis of splenic marginal zone lymphoma (SMZL) remains largely unknown. Recent high-throughput sequencing studies have identified recurrent mutations in key pathways, most notably NOTCH2 mutations in >25% of patients. These studies are based on small, heterogeneous discovery cohorts, a...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2013-12-13.
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Subjects: | |
Online Access: | Get fulltext |