Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma

The pathogenesis of splenic marginal zone lymphoma (SMZL) remains largely unknown. Recent high-throughput sequencing studies have identified recurrent mutations in key pathways, most notably NOTCH2 mutations in >25% of patients. These studies are based on small, heterogeneous discovery cohorts, a...

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Main Authors: Parry, Marina (Author), Rose-Zerilli, Matthew J. J. (Author), Gibson, Jane (Author), Ennis, Sarah (Author), Walewska, Renata (Author), Forster, Jade (Author), Parker, Helen (Author), Davis, Zadie (Author), Gardiner, Anne (Author), Collins, Andrew (Author), Oscier, David G. (Author), Strefford, Jonathan C. (Author)
Format: Article
Language:English
Published: 2013-12-13.
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