Article 2 Case-Control Studies 2 Female 2 Humans 2 Male 2 Middle Aged 2 RNA, Long Noncoding 2 Severity of Illness Index 2 adult blood 2 case control study 2 controlled study 2 cytokine 2 disease severity 2 female 2 gene expression 2 gene function 2 genetics 2 human 2 interleukin 17 2 interleukin 6 2 long untranslated RNA 2 major clinical study 2 male 2 middle aged 2 pathology 2 prognosis 2 real time reverse transcription polymerase chain reaction 2 risk assessment 2 risk factor 2