Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

by Lee, Kyungheon, Song, Jun, Weissleder, Ralph, Lee, Hakho, Chen, Sidi, Sanjana, Neville E, Zheng, Kaijie, Shalem, Ophir, Shi, Xi, Scott, David Arthur, Pan, Jennifer Q., Zhang, Feng, Sharp, Phillip A.
Published 2017

Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

by Lamming, Dudley W., Ye, Lan, Astle, Clinton M., Baur, Joseph A., Harrison, David E., Sabatini, David
Published 2015

Fine-Tuning of PI3K/AKT Signalling by the Tumour Suppressor PTEN Is Required for Maintenance of Flight Muscle Function and Mitochondrial Integrity in Ageing Adult Drosophila melano...

by Davison, Claire, Fan, Shih-Jung, Morris, John F., Goberdhan, Deborah C. I., Wilson, Clive, Mensah, Lawrence
Published 2017

Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

by Barnes, Carmen M., Khan, Omar Fizal, Zaia, Edmond, Jhunjhunwala, Siddharth, Xue, Wen, Yun, Dong Soo, Dahlman, James, Dong, Yizhou, Pelet, Jeisa, Webber, Matthew, Tsosie, Jonathan, Jacks, Tyler E., Langer, Robert S., Anderson, Daniel Griffith, Cai, Wenxin,M. Arch.Massachusetts Institute of Technology
Published 2016

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

by Lamming, Dudley W., Mihaylova, Maria M., Katajisto, Pekka, Baar, Emma L., Yilmaz, Omer, Hutchins, Amanda W., Gultekin, Yetis, Gaither, Rachel P., Sabatini, David M.
Published 2014

Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery

by Pridgen, Eric M., Alexis, Frank, Kuo, Timothy T., Levy-Nissenbaum, Etgar, Karnik, Rohit, Blumberg, Richard S., Langer, Robert, Farokhzad, Omid C.
Published 2015

Painting blood vessels and atherosclerotic plaques with an adhesive drug depot

by Kastrup, Christian, Nahrendorf, Matthias, Figueiredo, Jose Luiz, Lee, Haeshin, Kambhampati, Swetha, Lee, Timothy, Cho, Seung Woo, Gorbatov, Rostic, Iwamoto, Yoshiko, Dang, Tram T., Dutta, Partha, Yeon, Ju Hun, Cheng, Hao, Vegas, Arturo, Siegel, Cory D., MacDougall, Samantha, Okonkwo, Michael E., Thai, Anh, Stone, James R., Coury, Arthur J., Weissleder, Ralph, Langer, Robert, Anderson, Daniel Griffith, Pritchard, Christopher D., (Christopher David)
Published 2013

Neutrophil Responses to Sterile Implant Materials

by Jhunjhunwala, Siddharth, Tang, Katherine, Alvarez, David, Tang, Benjamin C., Lavin, Danya M., Veiseh, Omid, Bose, Suman, Vegas, Arturo, Ma, Minglin, Sahay, Gaurav, Chiu, Alan, Bader, Andrew, Langan, Erin, Li, Jie, Greiner, Dale L., Newburger, Peter E., von Andrian, Ulrich H., Webber, Matthew, Anderson, Daniel Griffith, Siebert, Sean M, Langer, Robert S, Aresta-Dasilva, Stephanie K, Doloff, Joshua C
Published 2015

Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

by Luna, Joseph M., Hoffmann, Hans.-Heinrich, Espiritu, Christine, Sheahan, Timothy P., Rice, Charles M., Ramanan, Vyas, Trehan, Kartik, Ong, Mei Lyn, Chandrasekar, Hamsika, Christine, Kathleen, van Oudenaarden, Alexander, Bhatia, Sangeeta N, Schwartz, Robert E.
Published 2017

A luminal unfolding microneedle injector for oral delivery of macromolecules

by Abramson, Alex, Caffarel Salvador, Ester, Soares, Vance, Minahan Jr, Daniel J, Tian, Ryan Yu, Lu, Xiaoya, Dellal, David (David M.), Gao, Yuan, Kim, Soyoung, Wainer, Jacob P, Collins, Joy E, Tamang, Siddartha M, Hayward, Alison M, Yoshitake, Tadayuki, Lee, Hsiang-Chieh, Fujimoto, James G, Fels, Johannes, Frederiksen, Morten Revsgaard, Rahbek, Ulrik, Roxhed, Niclas, Langer, Robert S, Traverso, Carlo Giovanni
Published 2021

In vivo genome editing using Staphylococcus aureus Cas9

by Ran, F. Ann, Cong, Le, Yan, Winston X., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene V., Sharp, Phillip A., Zhang, Feng, Yan, Winston Xia, Scott, David Arthur
Published 2016

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

by Miraldi, Emily Rae, Sharfi, Hadar, Friedline, Randall H., Johnson, Hannah, Zhang, Tejia, Lau, Ken S., Ko, Hwi Jin, Curran, Timothy G., Haigis, Kevin M., Yaffe, Michael B., Bonneau, Richard, Lauffenburger, Douglas A., Kahn, Barbara B., Kim, Jason K., Neel, Benjamin G., Saghatelian, Alan, White, Forest M.
Published 2014

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

by Li, Jie, Sasaki, Mika, Horner, James W, Burga, Laura N, Xie, Jianxin, Jurczak, Michael J, DePinho, Ronald A, Clish, Clary B, Kibbey, Richard G, Wulf, Gerburg M, Di Vizio, Dolores, Mills, Gordon B, Cantley, Lewis C, Israelsen, William James, Dayton, Talya L., Davidson, Shawn M., Fiske, Brian Prescott, Hosios, Aaron Marc, Bellinger, Gary, Yu, Yimin, Jacks, Tyler E., Vander Heiden, Matthew G.
Published 2017

Microgel encapsulated nanoparticles for glucose-responsive insulin delivery

by Volpatti, Lisa R, Facklam, Amanda L., Cortinas, Abel Bryan, Lu, Yen-Chun, Matranga, Morgan A., MacIsaac, Corina, Hill, Michael C., Langer, Robert S, Anderson, Daniel Griffith
Published 2021

Near-infrared-actuated devices for remotely controlled drug delivery

by Timko, Brian P., Arruebo, Manuel, Shankarappa, Sahadev A., McAlvin, J. Brian, Okonkwo, Obiajulu Stephanie, Mizrahi, Boaz, Stefanescu, Cristina F., Gomez, Leyre, Zhu, Jia, Santamaria, Jesus, Zhu, Angela W., Langer, Robert S, Kohane, Daniel S
Published 2014