Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

by Edurne Rujas, Daniel P. Leaman, Sara Insausti, Pablo Carravilla, Miguel García-Porras, Eneko Largo, Izaskun Morillo, Rubén Sánchez-Eugenia, Lei Zhang, Hong Cui, Ibon Iloro, Félix Elortza, Jean-Philippe Julien, Christian Eggeling, Michael B. Zwick, Jose M.M. Caaveiro, José L. Nieva
Published 2021-09-01

Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2

by Xingyue An, Melisa Martinez-Paniagua, Ali Rezvan, Samiur Rahman Sefat, Mohsen Fathi, Shailbala Singh, Sujit Biswas, Melissa Pourpak, Cassian Yee, Xinli Liu, Navin Varadarajan
Published 2021-09-01

Longitudinal analysis of severe acute respiratory syndrome coronavirus 2 seroprevalence using multiple serology platforms

by Juan Manuel Carreño, Damodara Rao Mendu, Viviana Simon, Masood A. Shariff, Gagandeep Singh, Vidya Menon, Florian Krammer
Published 2021-09-01

Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2

by Jun-Gyu Park, Fatai S. Oladunni, Mohammed A. Rohaim, Jayde Whittingham-Dowd, James Tollitt, Matthew D.J. Hodges, Nadin Fathallah, Muhsref Bakri Assas, Wafaa Alhazmi, Abdullah Almilaibary, Munir Iqbal, Pengxiang Chang, Renee Escalona, Vinay Shivanna, Jordi B. Torrelles, John J. Worthington, Lucy H. Jackson-Jones, Luis Martinez-Sobrido, Muhammad Munir
Published 2021-09-01

NK-B cell cross talk induces CXCR5 expression on natural killer cells

by Philippe Rascle, Béatrice Jacquelin, Caroline Petitdemange, Vanessa Contreras, Cyril Planchais, Marie Lazzerini, Nathalie Dereuddre-Bosquet, Roger Le Grand, Hugo Mouquet, Nicolas Huot, Michaela Müller-Trutwin
Published 2021-10-01

A new flow cytometry assay to measure antibody-dependent cellular cytotoxicity against SARS-CoV-2 Spike-expressing cells

by Guillaume Beaudoin-Bussières, Jonathan Richard, Jérémie Prévost, Guillaume Goyette, Andrés Finzi
Published 2021-12-01

SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway

by Grant R. Campbell, Rachel K. To, Jonathan Hanna, Stephen A. Spector
Published 2021-04-01

Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes

by Shengli Ding, Jing Yang, Xuehuan Feng, Aseem Pandey, Rola Barhoumi, Dongmei Zhang, Samantha L. Bell, Yue Liu, Luciana Fachini da Costa, Allison Rice-Ficht, Robert O. Watson, Kristin L. Patrick, Qing-Ming Qin, Thomas A. Ficht, Paul de Figueiredo
Published 2021-03-01

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

by Ziliang Zhou, Chunliu Huang, Zhechong Zhou, Zhaoxia Huang, Lili Su, Sisi Kang, Xiaoxue Chen, Qiuyue Chen, Suhua He, Xia Rong, Fei Xiao, Jun Chen, Shoudeng Chen
Published 2021-03-01

How a Latent Virus Eludes Immune Defenses

Published 2005-01-01

Gamma-Herpesvirus Latency Requires T Cell Evasion during Episome Maintenance

by Bennett Neil J, May Janet S, Stevenson Philip G
Published 2005-01-01

Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors

by Ana L. Portillo, Richard Hogg, Sophie M. Poznanski, Eduardo A. Rojas, Niamh J. Cashell, Joanne A. Hammill, Marianne V. Chew, Mira M. Shenouda, Tyrah M. Ritchie, Quynh T. Cao, Jeremy A. Hirota, Sukhbinder Dhesy-Thind, Jonathan L. Bramson, Ali A. Ashkar
Published 2021-06-01

Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

by Yuting Li, Zhen Li, Yumeng Quan, Hongyun Cheng, Manuel A. Riquelme, Xiao-Dong Li, Sumin Gu, Jean X. Jiang
Published 2021-06-01

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

by Camila O.S. Souza, Natália Ketelut-Carneiro, Cristiane M. Milanezi, Lúcia H. Faccioli, Luiz G. Gardinassi, João S. Silva
Published 2021-06-01

Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K+ leakage

by Karl-Jan Spittaels, Katleen van Uytfanghe, Christos C. Zouboulis, Christophe Stove, Aurélie Crabbé, Tom Coenye
Published 2021-06-01

NFAT signaling in human mesenchymal stromal cells affects extracellular matrix remodeling and antifungal immune responses

by Federico Tidu, Marco De Zuani, Shyam Sushama Jose, Kamila Bendíčková, Lukáš Kubala, Frank Caruso, Francesca Cavalieri, Giancarlo Forte, Jan Frič
Published 2021-06-01

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

by Arinjay Banerjee, Nader El-Sayes, Patrick Budylowski, Rajesh Abraham Jacob, Daniel Richard, Hassaan Maan, Jennifer A. Aguiar, Wael L. Demian, Kaushal Baid, Michael R. D'Agostino, Jann Catherine Ang, Tetyana Murdza, Benjamin J.-M. Tremblay, Sam Afkhami, Mehran Karimzadeh, Aaron T. Irving, Lily Yip, Mario Ostrowski, Jeremy A. Hirota, Robert Kozak, Terence D. Capellini, Matthew S. Miller, Bo Wang, Samira Mubareka, Allison J. McGeer, Andrew G. McArthur, Andrew C. Doxey, Karen Mossman
Published 2021-05-01

The Hygiene Hypothesis, Old Friends, and New Genes

by John W. Frew
Published 2019-03-01

Analysis of Global Gene Expression Changes in Human Bronchial Epithelial Cells Exposed to Spores of the Allergenic Fungus, Alternaria alternata

by Mihaela eBabiceanu, Mihaela eBabiceanu, Brad eHoward, Amanda eRumore, Amanda eRumore, Hirohito eKita, Christopher eLawrence
Published 2013-07-01

Acute renal allograft rejection: progress in understanding cellular and molecular mechanisms.

by Divate S
Published 2000-10-01