Signal Amplification in Highly Ordered Networks Is Driven by Geometry

by Faustman, D.L, Lippner, G., Vanamee, É.S
Published 2022

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

by Andrews, P., Arun, G., Bhatia, S., Brophy, K., Fan, C., Ha, T., Kostroff, K., Kramer, M., McCombie, W.R, Naik, P., Perou, C.M, Plenker, D., Preall, J., Rishi, A., Russo, S., Spector, D.L, Tuveson, D.A, Wilkinson, J.E
Published 2022

Approximation to pain-signaling network in humans by means of migraine

by Hosp, J.A, Reisert, M., Rijntjes, M., von Kageneck, C., Weiller, C.
Published 2021

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance

by Beule, D., Blanc, E., Blüthgen, N., Dorel, M., Eggert, A., Hertwig, F., Klinger, B., Mari, T., Messerschmidt, C., Nadler-Holly, M., Schulte, J.H, Selbach, M., Sieber, A., Toedling, J., Ziehm, M.
Published 2021

Cell-to-cell and type-to-type heterogeneity of signaling networks: insights from the crowd

by Bodenmiller, B., Cao, W., Chung, V., Driessen, A., Gabor, A., Guo, B., Saez-Rodriguez, J., Shen, H., Single Cell Signaling in Breast Cancer DREAM Consortium members, Tanevski, J., Tognetti, M., Yu, T.
Published 2021

Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway

by Chen, R., Gong, S., Hu, Q., Li, M., Xu, W., Zhang, B., Zhang, M., Zhang, Y., Zheng, Z.
Published 2022

Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation

by Beaudoin, A.J, Brivanlou, A.H, Carroll, T.S, De Santis, R., Etoc, F., Gnedeva, K., Haremaki, T., Hudspeth, A.J, Kastan, N.R, Laundos, T.L, Luo, J.-D, Piccolo, F.M, Tian, Q.
Published 2022

A systems genomics approach uncovers molecular associates of RSV severity

by Benoodt, L., Caserta, M.T, Chu, C.-Y, Corbett, A., Falsey, A.R, Gill, S.R, Grier, A., Holden-Wiltse, J., Mariani, T.J, McCall, M.N, Qiu, X., Slaunwhite, C., Thakar, J., Topham, D.J, Walsh, E.E, Wang, L.
Published 2021

Fine Particulate Matter Induces Childhood Asthma Attacks via Extracellular Vesicle-Packaged Let-7i-5p-Mediated Modulation of the MAPK Signaling Pathway

by Chu, H., Du, M., Gan, C., Gao, F., Liang, J., Mao, Z., Tian, M., Wang, M., Wei, C., Xue, R., Zhang, Z., Zheng, R., Zhu, Z.
Published 2022

The variations in human orphan G protein-coupled receptor QRFPR affect PI3K-AKT-mTOR signaling

by Hu, L., Li, H., Lin, X., Lou, R., Tang, S., Xiang, Y., Xu, C., Xu, X., Xu, Y., Yu, Y.
Published 2021

Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities

by Hong, H., Kim, J.K, Song, Y.M
Published 2021

Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy

by Jerath, G., Kartha, C.C, Kumar, V., Rai, A., Ramakrishnan, V.
Published 2021

Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells

by Ghanate, A.D, Immanuel, S.R.C, Panchagnula, V., Parmar, D.S, Raghunathan, A., Uthup, R., Yadav, R.
Published 2021

A highly multiplexed quantitative phosphosite assay for biology and preclinical studies

by Babur, O., Burgess, M., Carr, S.A, Forestier, D., Gillette, M.A, Golji, J., Jane-Valbuena, J., Jean Beltran, P.M, Keshishian, H., Krug, K., Kuhn, E., MacMullan, M.A, Mani, D.R, Marlow, S.E, McDonald, E.R., III, Melanson, R., Mundt, F., Olive, M.E, Porter, D.A, Rabasha, B., Rejtar, T., Robinson, M.L, Satpathy, S., Sellers, W.R, Specht, H., Todres, E., Wallace, L., Wang, K.
Published 2021

Inflammation associated with noise-induced hearing loss

by Frye, M.D, Kurabi, A., Ryan, A.F
Published 2019

Nested information processing in the living world

by Wurtz, T.
Published 2021

Estimating the dimensionality of the manifold underlying multi-electrode neural recordings

by Altan, E., Miller, L.E, Perreault, E.J, Solla, S.A
Published 2021

Multistability maintains redox homeostasis in human cells

by Chen, S.-H, Co, H.K.C, Huang, J.-H, Lee, Y.-C, Wu, C.-C
Published 2021

Seven computations of the social brain

by Friston, K., Hagan, C.C, Mobbs, D., Molapour, T., Ramstead, M., Silston, B., Wu, H.
Published 2021

Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection

by Alcaraz, N., Baumbach, J., Del Moral-Morales, A., González-Barrios, R., Navarro-Delgado, E.I, Salgado-Albarrán, M., Soto-Reyes, E.
Published 2021