human signal transduction Humans 7 Review 7 interleukin 6 4 metabolism 4 nonhuman 4 protein expression 4 tumor necrosis factor 4 unclassified drug 4 Article 3 cytokine 3 female 3 interleukin 1beta 3 interleukin 8 3 mitogen activated protein kinase 3 nervous system inflammation 3 pathology 3 protein function 3 protein phosphorylation 3 reactive oxygen metabolite 3 Alzheimer disease 2 Animals 2 Autism 2 Brain 2 Female 2 MAP Kinase Signaling System 2 Oxidative stress 2 Pregnancy 2 Proto-Oncogene Proteins c-akt 2