gene expression human Article 52 Humans 49 controlled study 46 genetics 43 female 37 real time polymerase chain reaction 35 male 33 adult 32 Female 31 Male 30 major clinical study 29 unclassified drug 27 middle aged 25 metabolism 24 Middle Aged 23 human cell 23 gene expression regulation 22 pathology 22 human tissue 20 upregulation 20 Gene Expression Regulation, Neoplastic 18 case control study 17 microRNA 17 prognosis 17 protein expression 17 real time reverse transcription polymerase chain reaction 17 blood 16 long untranslated RNA 16