Venetoclax, a BCL-2 Inhibitor, Enhances the Efficacy of Chemotherapeutic Agents in Wild-Type ABCG2-Overexpression-Mediated MDR Cancer Cells

by Jing-Quan Wang, Jonathan Y. Li, Qiu-Xu Teng, Zi-Ning Lei, Ning Ji, Qingbin Cui, Leli Zeng, Yihang Pan, Dong-Hua Yang, Zhe-Sheng Chen
Published 2020-02-01

Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance

by Xiaofang Luo, Qiu-Xu Teng, Jin-Yun Dong, Dong-Hua Yang, Meifeng Wang, Wubliker Dessie, Jiang-Jiang Qin, Zi-Ning Lei, Jing-Quan Wang, Zuodong Qin, Zhe-Sheng Chen
Published 2020-08-01

Erdafitinib Antagonizes ABCB1-Mediated Multidrug Resistance in Cancer Cells

by Weiguo Feng, Weiguo Feng, Meng Zhang, Meng Zhang, Zhuo-Xun Wu, Jing-Quan Wang, Xing-Duo Dong, Yuqi Yang, Qiu-Xu Teng, Xuan-Yu Chen, Xuan-Yu Chen, Qingbin Cui, Dong-Hua Yang
Published 2020-06-01

Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells

by Jingqiu Wang, Dong-Hua Yang, Yuqi Yang, Jing-Quan Wang, Chao-Yun Cai, Zi-Ning Lei, Qiu-Xu Teng, Zhuo-Xun Wu, Linguo Zhao, Zhe-Sheng Chen
Published 2020-02-01

Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells

by Xing-Duo Dong, Meng Zhang, Meng Zhang, Xiubin Ma, Jing-Quan Wang, Zi-Ning Lei, Qiu-Xu Teng, Yi-Dong Li, Lusheng Lin, Weiguo Feng, Weiguo Feng, Zhe-Sheng Chen
Published 2020-08-01

Establishment and Characterization of a Topotecan Resistant Non-small Cell Lung Cancer NCI-H460/TPT10 Cell Line

by Zi-Ning Lei, Qiu-Xu Teng, Wei Zhang, Wei Zhang, Ying-Fang Fan, Ying-Fang Fan, Jing-Quan Wang, Chao-Yun Cai, Kimberly W. Lu, Kimberly W. Lu, Dong-Hua Yang, John N. D. Wurpel, Zhe-Sheng Chen
Published 2020-12-01

VKNG-1 Antagonizes ABCG2-Mediated Multidrug Resistance via p-AKT and Bcl-2 Pathway in Colon Cancer: In Vitro and In Vivo Study

by Silpa Narayanan, Ying-Fang Fan, Nehaben A. Gujarati, Qiu-Xu Teng, Jing-Quan Wang, Chao-Yun Cai, Yuqi Yang, Anirudh J. Chintalapati, Yixiong Lei, Vijaya L. Korlipara, Zhe-Sheng Chen
Published 2021-09-01

Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells

by Yongchao Zhang, Zhuo-Xun Wu, Yuqi Yang, Jing-Quan Wang, Jun Li, Zoey Sun, Qiu-Xu Teng, Charles R. Ashby, Dong-Hua Yang
Published 2020-11-01

Reversal of Cancer Multidrug Resistance (MDR) Mediated by ATP-Binding Cassette Transporter G2 (ABCG2) by AZ-628, a RAF Kinase Inhibitor

by Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Ning Ji, Qingbin Cui, Qingbin Cui, Han Fu, Lizhu Lin, Dong-Hua Yang, Ying-Fang Fan, Ying-Fang Fan, Zhe-Sheng Chen
Published 2020-12-01

Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells

by Wei Zhang, Wei Zhang, Ying-Fang Fan, Ying-Fang Fan, Chao-Yun Cai, Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Leli Zeng, Leli Zeng, Pranav Gupta, Zhe-Sheng Chen
Published 2018-10-01

BMS-599626, a Highly Selective Pan-HER Kinase Inhibitor, Antagonizes ABCG2-Mediated Drug Resistance

by Yunali V. Ashar, Jingchun Zhou, Pranav Gupta, Qiu-Xu Teng, Zi-Ning Lei, Sandra E. Reznik, Sabrina Lusvarghi, John Wurpel, Suresh V. Ambudkar, Zhe-Sheng Chen
Published 2020-09-01

NVP-CGM097, an HDM2 Inhibitor, Antagonizes ATP-Binding Cassette Subfamily B Member 1-Mediated Drug Resistance

by Meng Zhang, Meng Zhang, Xuan-Yu Chen, Xuan-Yu Chen, Xing-Duo Dong, Jing-Quan Wang, Weiguo Feng, Weiguo Feng, Qiu-Xu Teng, Qingbin Cui, Jing Li, Xiang-Qi Li, Zhe-Sheng Chen
Published 2020-07-01