Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation

by Dettmer, Ulf, Newman, Andrew J., Soldner, Frank, Luth, Eric S., Kim, Nora C., von Saucken, Victoria E., Sanderson, John B., Jaenisch, Rudolf, Bartels, Tim, Selkoe, Dennis
Published 2015

Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

by Muratore, Christina R., Zhou, Constance, Liao, Meichen, Fernandez, Marty A., Taylor, Walter M., Lagomarsino, Valentina N., Pearse, Richard V. II, Rice, Heather C., Negri, Joseph M., He, Amy, Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Zhou, Monica, Bennett, David A., Noggle, Scott, Love, J. Christopher, Selkoe, Dennis J., Young-Pearse, Tracy L.
Published 2020

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

by Fanning, Saranna, Haque, Aftabul, Imberdis, Thibaut, Baru, Valeriya, Barrasa, M. Inmaculada, Nuber, Silke, Termine, Daniel, Ramalingam, Nagendran, Ho, Gary P.H, Noble, Tallie, Sandoe, Jackson, Lou, Yali, Landgraf, Dirk, Freyzon, Yelena, Newby, Gregory, Soldner, Frank, Terry-Kantor, Elizabeth, Kim, Tae-Eun, Hofbauer, Harald F., Becuwe, Michel, Jaenisch, Rudolf, Pincus, David, Clish, Clary B., Walther, Tobias C., Farese, Robert V., Srinivasan, Supriya, Welte, Michael A., Kohlwein, Sepp D., Dettmer, Ulf, Lindquist, Susan, Selkoe, Dennis
Published 2020