Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease

Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease

Parkinson's disease (PD) shows high heterogeneity with regard to the underlying molecular pathogenesis involving multiple pathways and mechanisms. Diagnosis is still challenging and rests entirely on clinical features. Thus, there is an urgent need for robust diagnostic biofluid markers. Untarg...

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Bibliographic Details
Main Authors: Daniel Stoessel, Claudia Schulte, Marcia C. Teixeira dos Santos, Dieter Scheller, Irene Rebollo-Mesa, Christian Deuschle, Dirk Walther, Nicolas Schauer, Daniela Berg, Andre Nogueira da Costa, Walter Maetzler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
biomarker
untargeted metabolomics
neurodegeneration
plasma
CSF
machine learning
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00051/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00051/full

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