Noradrenaline and Parkinson's disease

Parkinson’s disease (PD) is characterized by the degeneration of dopamine (DA) neurons in the substantia nigra pars compacta, and motor symptoms including bradykinesia, rigidity and tremor at rest. These symptoms are manifest when around 70% of striatal DA is lost. In addition to motor deficits, PD...

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Bibliographic Details
Main Authors: Claire eDelaville, Philippe eDe Deurwaerdère, Abdelhamid eBenazzouz
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00031/full