Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability?

Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability?

Adiponectin (APN) is a multi-functional adipokine which sensitizes the insulin signals, stimulates mitochondria biogenesis, and suppresses inflammation. By virtue of these beneficial properties, APN may protect against metabolic syndrome, including obesity and type II diabetes mellitus. Since these...

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Bibliographic Details
Main Authors: Masaaki Waragai, Gilbert Ho, Yoshiki Takamatsu, Ryoko Wada, Shuei Sugama, Takato Takenouchi, Eliezer Masliah, Makoto Hashimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Endocrinology
Subjects:
adiponectin
adiponectin paradox
chronic heart failure (CHF)
Alzheimer's disease (AD)
evolvability
antagonistic pleiotropy
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00108/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00108/full

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