Dectin-1-Mediated DC-SIGN Recruitment to <i>Candida albicans</i> Contact Sites

At host–pathogen contact sites with <i>Candida albicans</i>, Dectin-1 activates pro-inflammatory signaling, while DC-SIGN promotes adhesion to the fungal surface. We observed that Dectin-1 and DC-SIGN collaborate to enhance capture/retention of <i>C. albicans</i> under fluid...

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Bibliographic Details
Main Authors: Rohan P. Choraghe, Aaron K. Neumann
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/2/108