The 3D Genome as Moderator of Chromosomal Communication

Proper expression of genes requires communication with their regulatory elements that can be located elsewhere along the chromosome. The physics of chromatin fibers imposes a range of constraints on such communication. The molecular and biophysical mechanisms by which chromosomal communication is es...

Full description

Bibliographic Details
Main Authors: Dekker, Job (Author), Mirny, Leonid A (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-12-19T14:16:32Z.
Subjects:
Online Access:Get fulltext