Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension

Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension

Cells in a tumor microenvironment are exposed to spatial and temporal variations in oxygen tension due to hyperproliferation and immature vascularization. Such spatiotemporal oxygen heterogeneity affects the behavior of cancer cells, leading to cancer growth and metastasis, and thus, it is essential...

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Main Authors: Koens, Rei (Author), Tabata, Yugo (Author), Serrano, Jean Carlos (Author), Aratake, Satoshi (Author), Yoshino, Daisuke (Author), Kamm, Roger Dale (Author), Funamoto, Kenichi (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: AIP Publishing, 2020-11-05T20:02:03Z.
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