Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer’s disease

We previously showed that simvastatin (SV) restored memory in a mouse model of Alzheimer disease (AD) concomitantly with normalization in protein levels of memory-related immediate early genes in hippocampal CA1 neurons. Here, we investigated age-related changes in the hippocampal memory pathway, an...

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Bibliographic Details
Main Authors: Hamel, E. (Author), Royea, J. (Author), Tong, X.-K (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
Online Access:View Fulltext in Publisher