Search Results - Alan Mackay-Sim

Alan Mackay-Sim

Mackay-Sim in 2017 Alan Mackay-Sim (16 May 1951 – 4 January 2023) was an Australian biomedical scientist specialising in adult stem cell research, and winner of the 2017 Australian of the Year. Some of his research focused on olfactory ensheathing cells, which are cells in the human nose that interact with the nervous system to cause a sense of smell.

His research into stem cells contributed to the treatment of spinal cord injuries. The restoration of mobility to Darek Fidyka, a Polish paraplegic man, used research by Mackay-Sim. Provided by Wikipedia
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  1. 1

    Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery by Alan Mackay-Sim

    Published in Brain Sciences (2021-03-01)
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  2. 2

    Patient-Derived Stem Cell Models in SPAST HSP: Disease Modelling and Drug Discovery by Gautam Wali, Carolyn M. Sue, Alan Mackay-Sim

    Published in Brain Sciences (2018-07-01)
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  3. 3

    Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction by Cameron McDonald, Alan Mackay-Sim, Denis Crane, Wayne Murrell

    Published in The Scientific World Journal (2010-01-01)
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  4. 4

    Leukaemia inhibitory factor stimulates proliferation of olfactory neuronal progenitors via inducible nitric oxide synthase. by Estefania Lopez-Arenas, Alan Mackay-Sim, Juan Bacigalupo, Lorena Sulz

    Published in PLoS ONE (2012-01-01)
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  5. 5

    Transplantation of neuronal-primed human bone marrow mesenchymal stem cells in hemiparkinsonian rodents. by Melissa L M Khoo, Helen Tao, Adrian C B Meedeniya, Alan Mackay-Sim, David D F Ma

    Published in PLoS ONE (2011-01-01)
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  6. 6

    Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis. by Shane Stegeman, Lachlan A Jolly, Susitha Premarathne, Jozef Gecz, Linda J Richards, Alan Mackay-Sim, Stephen A Wood

    Published in PLoS ONE (2013-01-01)
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  7. 7

    Reduced acetylated α-tubulin in SPAST hereditary spastic paraplegia patient PBMCs by Gautam Wali, Gautam Wali, Gautam Wali, Sue-Faye Siow, Sue-Faye Siow, Erandhi Liyanage, Erandhi Liyanage, Kishore R. Kumar, Kishore R. Kumar, Kishore R. Kumar, Alan Mackay-Sim, Alan Mackay-Sim, Carolyn M. Sue, Carolyn M. Sue, Carolyn M. Sue

    Published in Frontiers in Neuroscience (2023-03-01)
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  8. 8

    Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern by Nicholas Matigian, Gary Brooke, Faten Zaibak, Tony Rossetti, Katarina Kollar, Rebecca Pelekanos, Celena Heazlewood, Alan Mackay-Sim, Christine A. Wells, Kerry Atkinson

    Published in Genomics Data (2015-03-01)
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  9. 9

    DNA methylation in schizophrenia in different patient-derived cell types by Alejandra M. Vitale, Nicholas A. Matigian, Alexandre S. Cristino, Katia Nones, Sugandha Ravishankar, Bernadette Bellette, Yongjun Fan, Stephen A. Wood, Ernst Wolvetang, Alan Mackay-Sim

    Published in npj Schizophrenia (2017-01-01)
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  10. 10

    Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress by Hannah C. Leeson, Julio Aguado, Cecilia Gómez-Inclán, Harman Kaur Chaggar, Atefah Taherian Fard, Zoe Hunter, Martin F. Lavin, Alan Mackay-Sim, Ernst J. Wolvetang

    Published in Neurobiology of Disease (2024-09-01)
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  11. 11

    Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients by Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen, Francisco Fernández Acosta, Marcela Cruz-Haces, Heikki Löppönen, Alan Mackay-Sim, Minna U. Kaikkonen, Anne M. Koivisto, Tarja Malm, Anthony R. White, Rosalba Giugno, Sweelin Chew, Katja M. Kanninen

    Published in Cells (2022-02-01)
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  12. 12

    An Alzheimer’s Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition by Laura M. Rantanen, Maina Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek, Lotta E. Oikari, Carla Cunί-Lόpez, Ratneswary Sutharsan, Gayathri Thillaiyampalam, Jamila Iqbal, Daniel Russell, Elina Penttilä, Heikki Löppönen, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Anne M. Koivisto, Larisa M. Haupt, Alan Mackay-Sim, Alexandre S. Cristino, Katja M. Kanninen, Anthony R. White

    Published in Cells (2022-10-01)
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