Search Results - Anne E. Carpenter
Anne E. Carpenter
Anne E. Carpenter is an American scientist in the field of image analysis for cell biology and artificial intelligence for drug discovery. She is the co-creator of CellProfiler, open-source software for high-throughput biological image analysis, and a co-inventor of the Cell Painting assay, a method for image-based profiling. She is an Institute Scientist and Senior Director of the Imaging Platform at the Broad Institute.
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Bridging Domain and Data by Anne E. Carpenter
Published in Patterns (2020-07-01)Get full text
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Systematic morphological profiling of human gene and allele function via Cell Painting by Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia B Berthet, Mark-Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S Boehm, Anne E Carpenter
Published in eLife (2017-03-01)Get full text
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Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects. by Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark-Anthony Bray, Federica Piccioni, David E Root, John G Doench, Jesse S Boehm, Anne E Carpenter
Published in PLoS ONE (2015-01-01)Get full text
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Predicting compound activity from phenotypic profiles and chemical structures by Nikita Moshkov, Tim Becker, Kevin Yang, Peter Horvath, Vlado Dancik, Bridget K. Wagner, Paul A. Clemons, Shantanu Singh, Anne E. Carpenter, Juan C. Caicedo
Published in Nature Communications (2023-04-01)Get full text
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High-content microscopy reveals a morphological signature of bortezomib resistance by Megan E Kelley, Adi Y Berman, David R Stirling, Beth A Cimini, Yu Han, Shantanu Singh, Anne E Carpenter, Tarun M Kapoor, Gregory P Way
Published in eLife (2023-09-01)Get full text
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A versatile information retrieval framework for evaluating profile strength and similarity by Alexandr A. Kalinin, John Arevalo, Erik Serrano, Loan Vulliard, Hillary Tsang, Michael Bornholdt, Alán F. Muñoz, Suganya Sivagurunathan, Bartek Rajwa, Anne E. Carpenter, Gregory P. Way, Shantanu Singh
Published in Nature Communications (2025-06-01)Get full text
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Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth. by Sarah A Stanley, Amy K Barczak, Melanie R Silvis, Samantha S Luo, Kimberly Sogi, Martha Vokes, Mark-Anthony Bray, Anne E Carpenter, Christopher B Moore, Noman Siddiqi, Eric J Rubin, Deborah T Hung
Published in PLoS Pathogens (2014-02-01)Get full text
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Combining phenomics with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion by Matthew Tegtmeyer, Dhara Liyanage, Yu Han, Kathryn B. Hebert, Ruifan Pei, Gregory P. Way, Pearl V. Ryder, Derek Hawes, Callum Tromans-Coia, Beth A. Cimini, Anne E. Carpenter, Shantanu Singh, Ralda Nehme
Published in Nature Communications (2025-07-01)Get full text
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Learning representations for image-based profiling of perturbations by Nikita Moshkov, Michael Bornholdt, Santiago Benoit, Matthew Smith, Claire McQuin, Allen Goodman, Rebecca A. Senft, Yu Han, Mehrtash Babadi, Peter Horvath, Beth A. Cimini, Anne E. Carpenter, Shantanu Singh, Juan C. Caicedo
Published in Nature Communications (2024-02-01)Get full text
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CellProfiler 3.0: Next-generation image processing for biology. by Claire McQuin, Allen Goodman, Vasiliy Chernyshev, Lee Kamentsky, Beth A Cimini, Kyle W Karhohs, Minh Doan, Liya Ding, Susanne M Rafelski, Derek Thirstrup, Winfried Wiegraebe, Shantanu Singh, Tim Becker, Juan C Caicedo, Anne E Carpenter
Published in PLoS Biology (2018-07-01)Get full text
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High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly by Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett
Published in eLife (2023-04-01)Get full text
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A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport by Evgeny Shlevkov, Himanish Basu, Mark-Anthony Bray, Zheng Sun, Wei Wei, Kaan Apaydin, Kyle Karhohs, Pin-Fang Chen, Janell L.M. Smith, Ole Wiskow, Kasper Roet, Xuan Huang, Kevin Eggan, Anne E. Carpenter, Robin J. Kleiman, Thomas L. Schwarz
Published in Cell Reports (2019-09-01)Get full text
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Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence. by Amy K Barczak, Roi Avraham, Shantanu Singh, Samantha S Luo, Wei Ran Zhang, Mark-Anthony Bray, Amelia E Hinman, Matthew Thompson, Raymond M Nietupski, Aaron Golas, Paul Montgomery, Michael Fitzgerald, Roger S Smith, Dylan W White, Anna D Tischler, Anne E Carpenter, Deborah T Hung
Published in PLoS Pathogens (2017-05-01)Get full text
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High-dimensional phenotyping to define the genetic basis of cellular morphology by Matthew Tegtmeyer, Jatin Arora, Samira Asgari, Beth A. Cimini, Ajay Nadig, Emily Peirent, Dhara Liyanage, Gregory P. Way, Erin Weisbart, Aparna Nathan, Tiffany Amariuta, Kevin Eggan, Marzieh Haghighi, Steven A. McCarroll, Luke O’Connor, Anne E. Carpenter, Shantanu Singh, Ralda Nehme, Soumya Raychaudhuri
Published in Nature Communications (2024-01-01)Get full text
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