A versatile information retrieval framework for evaluating profile strength and similarity

Abstract Large-scale profiling assays capture a cell population’s state by measuring thousands of biological properties per cell or sample. However, evaluating profile strength and similarity remains challenging due to the high dimensionality and non-linear, heterogeneous nature of measurements. Her...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Alexandr A. Kalinin, John Arevalo, Erik Serrano, Loan Vulliard, Hillary Tsang, Michael Bornholdt, Alán F. Muñoz, Suganya Sivagurunathan, Bartek Rajwa, Anne E. Carpenter, Gregory P. Way, Shantanu Singh
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Online Access:	https://doi.org/10.1038/s41467-025-60306-2