Search Results - Carsten Hoffmann
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GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner by Arnelle Löbbert, Nils Lorz, Edda S. F. Matthees, Philip Rößler, Carsten Hoffmann, Alvar D. Gossert
Published in Communications Biology (2025-06-01)Get full text
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Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation by Carlo Matera, Michael Kauk, Davide Cirillo, Marco Maspero, Claudio Papotto, Daniela Volpato, Ulrike Holzgrabe, Marco De Amici, Carsten Hoffmann, Clelia Dallanoce
Published in Molecules (2023-03-01)Get full text
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β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells by Raphael S. Haider, Edda S. F. Matthees, Julia Drube, Mona Reichel, Ulrike Zabel, Asuka Inoue, Andy Chevigné, Cornelius Krasel, Xavier Deupi, Carsten Hoffmann
Published in Nature Communications (2022-09-01)Get full text
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Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited by Owen Underwood, Sebastian Fritzwanker, Jaqueline Glenn, Nina Kathleen Blum, Arisbel Batista-Gondin, Julia Drube, Carsten Hoffmann, Stephen J. Briddon, Stefan Schulz, Meritxell Canals
Published in Communications Biology (2024-08-01)Get full text
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Helix-bundle and C-terminal GPCR domains differentially influence GRK-specific functions and β-arrestin-mediated regulation by Edda S. F. Matthees, Raphael S. Haider, Laura Klement, Mona Reichel, Nina K. Blum, Verena Weitzel, Thimea Trüpschuch, Carla Ziegler, Julia Drube, Stefan Schulz, Carsten Hoffmann
Published in Nature Communications (2025-07-01)Get full text
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Non-canonical internalization mechanisms of mGlu receptors by Marta Cimadevila, Junke Liu, Damien Maurel, Isabelle Brabet, Marine Hoscar, Julia Drube, Carsten Hoffmann, Asuka Inoue, Philippe Rondard, Pierre-André Lafon, Laurent Prézeau, Jean-Philippe Pin
Published in Cell Reports (2025-08-01)Get full text
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High-fat diet impairs microbial metabolite production and aggravates influenza A infection by Franziska Hornung, Harini K. SureshKumar, Laura Klement, Yasmina Reisser, Christoph Wernike, Vivien Nischang, Paul M. Jordan, Oliver Werz, Carsten Hoffmann, Bettina Löffler, Stefanie Deinhardt-Emmer
Published in Cell Communication and Signaling (2025-07-01)Get full text
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Reply to: How carvedilol does not activate β2-adrenoceptors by Evi Kostenis, Jesus Gomeza, Elke Miess-Tanneberg, Nina Kathleen Blum, Tobias Benkel, Andy Chevigné, Carsten Hoffmann, Peter Kolb, Viacheslav Nikolaev, Maria Waldhoer, Martyna Szpakowska, Asuka Inoue, Stefan Schulz
Published in Nature Communications (2023-11-01)Get full text
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Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia by Elke Butt, Katrin Stempfle, Lorenz Lister, Felix Wolf, Marcella Kraft, Andreas B. Herrmann, Cristina Perpina Viciano, Christian Weber, Andreas Hochhaus, Thomas Ernst, Carsten Hoffmann, Alma Zernecke, Jochen J. Frietsch
Published in Cells (2020-02-01)Get full text
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GRK specificity and Gβγ dependency determines the potential of a GPCR for arrestin-biased agonism by Edda S. F. Matthees, Jenny C. Filor, Natasha Jaiswal, Mona Reichel, Noureldine Youssef, Giulia D’Uonnolo, Martyna Szpakowska, Julia Drube, Gabriele M. König, Evi Kostenis, Andy Chevigné, Amod Godbole, Carsten Hoffmann
Published in Communications Biology (2024-07-01)Get full text
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A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening by Johanna Kaufmann, Nina Kathleen Blum, Falko Nagel, Anna Schuler, Julia Drube, Carsten Degenhart, Julian Engel, Jan Eicke Eickhoff, Pooja Dasgupta, Sebastian Fritzwanker, Maria Guastadisegni, Clemens Schulte, Elke Miess-Tanneberg, Hans Michael Maric, Mariana Spetea, Andrea Kliewer, Matthias Baumann, Bert Klebl, Rainer K. Reinscheid, Carsten Hoffmann, Stefan Schulz
Published in Communications Biology (2022-11-01)Get full text
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How Carvedilol activates β2-adrenoceptors by Tobias Benkel, Mirjam Zimmermann, Julian Zeiner, Sergi Bravo, Nicole Merten, Victor Jun Yu Lim, Edda Sofie Fabienne Matthees, Julia Drube, Elke Miess-Tanneberg, Daniela Malan, Martyna Szpakowska, Stefania Monteleone, Jak Grimes, Zsombor Koszegi, Yann Lanoiselée, Shannon O’Brien, Nikoleta Pavlaki, Nadine Dobberstein, Asuka Inoue, Viacheslav Nikolaev, Davide Calebiro, Andy Chevigné, Philipp Sasse, Stefan Schulz, Carsten Hoffmann, Peter Kolb, Maria Waldhoer, Katharina Simon, Jesus Gomeza, Evi Kostenis
Published in Nature Communications (2022-11-01)Get full text
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The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability by Niklas Ravn-Boess, Nainita Roy, Takamitsu Hattori, Devin Bready, Hayley Donaldson, Christopher Lawson, Cathryn Lapierre, Aryeh Korman, Tori Rodrick, Enze Liu, Joshua D. Frenster, Gabriele Stephan, Jordan Wilcox, Alexis D. Corrado, Julia Cai, Rebecca Ronnen, Shuai Wang, Sara Haddock, Jonathan Sabio Ortiz, Orin Mishkit, Alireza Khodadadi-Jamayran, Aris Tsirigos, David Fenyö, David Zagzag, Julia Drube, Carsten Hoffmann, Fabiana Perna, Drew R. Jones, Richard Possemato, Akiko Koide, Shohei Koide, Christopher Y. Park, Dimitris G. Placantonakis
Published in Cell Reports (2023-11-01)Get full text
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