Search Results - Christian Frezza

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  1. 1

    Genome and metabolome: chance and necessity by Emanuel Gonçalves, Christian Frezza

    Published in Genome Biology (2021-09-01)
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  2. 2

    Astrocyte power fuels neurons during stroke by Stefano Pluchino, Luca Peruzzotti-Jametti, Christian Frezza

    Published in Swiss Medical Weekly (2016-11-01)
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  3. 3

    Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation by Magdalena Koziol, Charles Bradshaw, George Allen, Ana Costa, Christian Frezza

    Published in Bio-Protocol (2016-11-01)
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  4. 4

    SiRCle (Signature Regulatory Clustering) model integration reveals mechanisms of phenotype regulation in renal cancer by Ariane Mora, Christina Schmidt, Brad Balderson, Christian Frezza, Mikael Bodén

    Published in Genome Medicine (2024-12-01)
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  5. 5

    Predicting selective drug targets in cancer through metabolic networks by Ori Folger, Livnat Jerby, Christian Frezza, Eyal Gottlieb, Eytan Ruppin, Tomer Shlomi

    Published in Molecular Systems Biology (2011-06-01)
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  6. 6

    Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues by Marlous Kamp, Jakub Surmacki, Marc Segarra Mondejar, Tim Young, Karolina Chrabaszcz, Fadwa Joud, Vincent Zecchini, Alyson Speed, Christian Frezza, Sarah E. Bohndiek

    Published in Nature Communications (2024-06-01)
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  7. 7

    A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration by Keren Yizhak, Sylvia E Le Dévédec, Vasiliki Maria Rogkoti, Franziska Baenke, Vincent C de Boer, Christian Frezza, Almut Schulze, Bob van de Water, Eytan Ruppin

    Published in Molecular Systems Biology (2014-08-01)
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  8. 8

    A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration by Keren Yizhak, Sylvia E Le Dévédec, Vasiliki Maria Rogkoti, Franziska Baenke, Vincent C deBoer, Christian Frezza, Almut Schulze, Bob van deWater, Eytan Ruppin

    Published in Molecular Systems Biology (2014-11-01)
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  9. 9

    Impact of mtG3PDH inhibitors on proliferation and metabolism of androgen receptor-negative prostate cancer cells: Role of extracellular pyruvate. by Floriana Jessica Di Paola, Luiza Hd Cardoso, Efterpi Nikitopoulou, Bianca Kulik, Sandra Rühl, Alexander Eva, Natascha Sommer, Thomas Linn, Erich Gnaiger, Klaus Failing, Kathrin Büttner, Christian Frezza, Sybille Mazurek

    Published in PLoS ONE (2025-01-01)
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  10. 10

    Impact of mtG3PDH inhibitors on proliferation and metabolism of androgen receptor-negative prostate cancer cells: Role of extracellular pyruvate by Floriana Jessica Di Paola, Luiza HD Cardoso, Efterpi Nikitopoulou, Bianca Kulik, Sandra Rühl, Alexander Eva, Natascha Sommer, Thomas Linn, Erich Gnaiger, Klaus Failing, Kathrin Büttner, Christian Frezza, Sybille Mazurek

    Published in PLoS ONE (2025-01-01)
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  11. 11

    FOXA2 controls the anti-oxidant response in FH-deficient cells by Connor Rogerson, Marco Sciacovelli, Lucas A. Maddalena, Andromachi Pouikli, Marc Segarra-Mondejar, Lorea Valcarcel-Jimenez, Christina Schmidt, Ming Yang, Elena Ivanova, Joshua Kent, Ariane Mora, Danya Cheeseman, Jason S. Carroll, Gavin Kelsey, Christian Frezza

    Published in Cell Reports (2023-07-01)
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  12. 12

    Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism by Dylan Gerard Ryan, Ming Yang, Hiran A Prag, Giovanny Rodriguez Blanco, Efterpi Nikitopoulou, Marc Segarra-Mondejar, Christopher A Powell, Tim Young, Nils Burger, Jan Lj Miljkovic, Michal Minczuk, Michael P Murphy, Alex von Kriegsheim, Christian Frezza

    Published in eLife (2021-12-01)
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  13. 13

    Metabolomic Profiling in Acute ST‐Segment–Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia–Reperfusion Injury by Matthias Kohlhauer, Sam Dawkins, Ana S. H. Costa, Regent Lee, Timothy Young, Victoria R. Pell, Robin P. Choudhury, Adrian P. Banning, Rajesh K. Kharbanda, Kourosh Saeb‐Parsy, Michael P. Murphy, Christian Frezza, Thomas Krieg, Keith M. Channon

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  14. 14

    Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression by Sara Clerici, Christine Podrini, Davide Stefanoni, Gianfranco Distefano, Laura Cassina, Maria Elena Steidl, Laura Tronci, Tamara Canu, Marco Chiaravalli, Daniel Spies, Thomas A Bell, Ana SH Costa, Antonio Esposito, Angelo D’Alessandro, Christian Frezza, Angela Bachi, Alessandra Boletta

    Published in EMBO Molecular Medicine (2024-04-01)
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  15. 15

    Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke by Amin Mottahedin, Hiran A. Prag, Andreas Dannhorn, Richard Mair, Christina Schmidt, Ming Yang, Annabel Sorby-Adams, Jordan J. Lee, Nils Burger, Duvaraka Kulaveerasingam, Margaret M. Huang, Stefano Pluchino, Luca Peruzzotti-Jametti, Richard Goodwin, Christian Frezza, Michael P. Murphy, Thomas Krieg

    Published in Redox Biology (2023-02-01)
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  16. 16

    Mutations in mitochondrial DNA causing tubulointerstitial kidney disease. by Thomas M Connor, Simon Hoer, Andrew Mallett, Daniel P Gale, Aurora Gomez-Duran, Viktor Posse, Robin Antrobus, Pablo Moreno, Marco Sciacovelli, Christian Frezza, Jennifer Duff, Neil S Sheerin, John A Sayer, Margaret Ashcroft, Michael S Wiesener, Gavin Hudson, Claes M Gustafsson, Patrick F Chinnery, Patrick H Maxwell

    Published in PLoS Genetics (2017-03-01)
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  17. 17

    Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses by Aurelien Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Attila Gabor, Kristina B. Emdal, Vitor Vieira, Dorte B. Bekker‐Jensen, Jennifer Kranz, Eric.M.J. Bindels, Ana S.H. Costa, Abel Sousa, Pedro Beltrao, Miguel Rocha, Jesper V. Olsen, Christian Frezza, Rafael Kramann, Julio Saez‐Rodriguez

    Published in Molecular Systems Biology (2021-01-01)
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  18. 18

    Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses by Mimmi LE Lundahl, Morgane Mitermite, Dylan Gerard Ryan, Sarah Case, Niamh C Williams, Ming Yang, Roisin I Lynch, Eimear Lagan, Filipa M Lebre, Aoife L Gorman, Bojan Stojkovic, Adrian P Bracken, Christian Frezza, Frederick J Sheedy, Eoin M Scanlan, Luke AJ O'Neill, Stephen V Gordon, Ed C Lavelle

    Published in eLife (2022-09-01)
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  19. 19

    Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression by Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S. H. Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R. Zecchini, Sabrina H. Rossi, Charlie Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent Gnanapragasam, Anne Y. Warren, Grant D. Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza

    Published in Nature Communications (2022-12-01)
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  20. 20

    Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system by Cherif Badja, Sophie Momen, Gene Ching Chiek Koh, Soraya Boushaki, Theodoros I. Roumeliotis, Zuza Kozik, Ian Jones, Vicky Bousgouni, João M.L. Dias, Marios G. Krokidis, Jamie Young, Hongwei Chen, Ming Yang, France Docquier, Yasin Memari, Lorea Valcarcel-Zimenez, Komal Gupta, Li Ren Kong, Heather Fawcett, Florian Robert, Salome Zhao, Andrea Degasperi, Yogesh Kumar, Helen Davies, Rebecca Harris, Christian Frezza, Chryssostomos Chatgilialoglu, Robert Sarkany, Alan Lehmann, Chris Bakal, Jyoti Choudhary, Hiva Fassihi, Serena Nik-Zainal

    Published in Cell Reports (2024-06-01)
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