Search Results - Christophe Deben

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  1. 1

    Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects by Jinthe Van Loenhout, Marc Peeters, Annemie Bogaerts, Evelien Smits, Christophe Deben

    Published in Antioxidants (2020-11-01)
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  2. 2

    STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy by Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde

    Published in Advanced Science (2025-05-01)
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  3. 3

    CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles by Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer

    Published in Journal of Translational Medicine (2024-03-01)
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  4. 4

    Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation by Ruben Verloy, Angela Privat-Maldonado, Jonas Van Audenaerde, Sophie Rovers, Hannah Zaryouh, Jorrit De Waele, Delphine Quatannens, Dieter Peeters, Geert Roeyen, Christophe Deben, Evelien Smits, Annemie Bogaerts

    Published in Cells (2025-03-01)
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  5. 5

    Functional Validation of the Putative Oncogenic Activity of <i>PLAU</i> by Federica Sarno, Désirée Goubert, Emilie Logie, Martijn G. S. Rutten, Mihaly Koncz, Christophe Deben, Anita E. Niemarkt, Lucia Altucci, Pernette J. Verschure, Antal Kiss, Wim Vanden Berghe, Marianne G. Rots

    Published in Biomedicines (2022-12-01)
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  6. 6

    In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53 by Jolien Van denBossche, Christophe Deben, Ines De Pauw, Hilde Lambrechts, Christophe Hermans, Vanessa Deschoolmeester, Julie Jacobs, Pol Specenier, Patrick Pauwels, Jan Baptist Vermorken, Marc Peeters, Filip Lardon, An Wouters

    Published in Molecular Oncology (2019-05-01)
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  7. 7

    Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers by Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Christophe Hermans, Céline Merlin, Ho Wa Lau, Elly Marcq, Marlies Verschuuren, Winnok H. De Vos, Filip Lardon, Evelien L. J. Smits, Christophe Deben

    Published in Antioxidants (2023-03-01)
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  8. 8

    Deep sequencing of the gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of variants by Christophe Deben, Jolien Van den Bossche, Nele Van Der Steen, Filip Lardon, An Wouters, Ken Op de Beeck, Christophe Hermans, Julie Jacobs, Marc Peeters, Guy Van Camp, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels

    Published in Tumor Biology (2017-02-01)
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  9. 9

    Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma by Jinthe Van Loenhout, Laurie Freire Boullosa, Delphine Quatannens, Jorrit De Waele, Céline Merlin, Hilde Lambrechts, Ho Wa Lau, Christophe Hermans, Abraham Lin, Filip Lardon, Marc Peeters, Annemie Bogaerts, Evelien Smits, Christophe Deben

    Published in Cells (2021-10-01)
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  10. 10

    Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model by Laurie Freire Boullosa, Jinthe Van Loenhout, Christophe Hermans, Ho Wa Lau, Céline Merlin, Elly Marcq, Farnaz Sedigheh Takhsha, Wim Martinet, Guido R. Y. De Meyer, Filip Lardon, Evelien L. J. Smits, Christophe Deben

    Published in Pharmaceutics (2022-12-01)
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  11. 11

    Development and validation of the Normalized Organoid Growth Rate (NOGR) metric in brightfield imaging-based assays by Christophe Deben, Edgar Cardenas De La Hoz, Felicia Rodrigues Fortes, Maxim Le Compte, Sofie Seghers, Steve Vanlanduit, Hendrik Vercammen, Bert Van Den Bogert, Nelson Dusetti, Abraham Lin, Geert Roeyen, Marc Peeters, Hans Prenen, Filip Lardon, Evelien Smits

    Published in Communications Biology (2024-12-01)
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  12. 12

    Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer by Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, Felicia Rodrigues Fortes, Christophe Hermans, Andreas Domen, Evelien Smits, Filip Lardon, Timon Vandamme, Abraham Lin, Steve Vanlanduit, Geert Roeyen, Steven Van Laere, Hans Prenen, Marc Peeters, Christophe Deben

    Published in npj Precision Oncology (2023-12-01)
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  13. 13

    Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition by Christophe Deben, Laurie Freire Boullosa, Felicia Rodrigues Fortes, Edgar Cardenas De La Hoz, Maxim Le Compte, Sofie Seghers, Marc Peeters, Steve Vanlanduit, Abraham Lin, Krijn K. Dijkstra, Paul Van Schil, Jeroen M. H. Hendriks, Hans Prenen, Geert Roeyen, Filip Lardon, Evelien Smits

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  14. 14

    IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts by Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Hilde Lambrechts, Tal Flieswasser, Delphine Quatannens, Gils Roex, Karen Zwaenepoel, Elly Marcq, Philippe Joye, Edgar Cardenas De La Hoz, Christophe Deben, Alessia Gasparini, Pierre Montay-Gruel, Maxim Le Compte, Eva Lion, Filip Lardon, Steven Van Laere, Vasiliki Siozopoulou, Diana Campillo-Davo, Jorrit De Waele, Patrick Pauwels, Julie Jacobs, Evelien Smits, Jonas R. M. Van Audenaerde

    Published in Journal of Hematology & Oncology (2024-02-01)
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