Search Results - Christopher J Lengner

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  1. 1

    Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish by Alexander J. Valvezan, Jian Huang, Christopher J. Lengner, Michael Pack, Peter S. Klein

    Published in Disease Models & Mechanisms (2014-01-01)
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  2. 2

    Single-Cell Analysis of Proxy Reporter Allele-Marked Epithelial Cells Establishes Intestinal Stem Cell Hierarchy by Ning Li, Maryam Yousefi, Angela Nakauka-Ddamba, Rajan Jain, John Tobias, Jonathan A. Epstein, Shane T. Jensen, Christopher J. Lengner

    Published in Stem Cell Reports (2014-11-01)
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  3. 3

    Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells by Maryam Yousefi, Angela Nakauka-Ddamba, Corbett T. Berry, Ning Li, Jenna Schoenberger, Kamen P. Simeonov, Ryan J. Cedeno, Zhengquan Yu, Christopher J. Lengner

    Published in Stem Cell Reports (2018-03-01)
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  4. 4

    Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids by Hongwon Kim, Hyeok Ju Park, Hwan Choi, Yujung Chang, Hanseul Park, Jaein Shin, Junyeop Kim, Christopher J. Lengner, Yong Kyu Lee, Jongpil Kim

    Published in Stem Cell Reports (2019-03-01)
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  5. 5

    LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3 by Kensuke Sugiura, Yasunori Masuike, Kensuke Suzuki, Alice E. Shin, Nozomu Sakai, Hisahiro Matsubara, Masayuki Otsuka, Peter A. Sims, Christopher J. Lengner, Anil K. Rustgi

    Published in JCI Insight (2023-07-01)
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  6. 6

    The Tumor Suppressor <i>Adenomatous Polyposis Coli (apc)</i> Is Required for Neural Crest-Dependent Craniofacial Development in Zebrafish by Xiaolei Liu, William D. Jones, Mathieu Quesnel-Vallières, Sudhish A. Devadiga, Kristin Lorent, Alexander J. Valvezan, Rebecca L. Myers, Ning Li, Christopher J. Lengner, Yoseph Barash, Michael Pack, Peter S. Klein

    Published in Journal of Developmental Biology (2023-06-01)
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  7. 7

    Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state by Yarden Katz, Feifei Li, Nicole J Lambert, Ethan S Sokol, Wai-Leong Tam, Albert W Cheng, Edoardo M Airoldi, Christopher J Lengner, Piyush B Gupta, Zhengquan Yu, Rudolf Jaenisch, Christopher B Burge

    Published in eLife (2014-11-01)
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  8. 8

    LIN28B-mediated PI3K/AKT pathway activation promotes metastasis in colorectal cancer models by Alice E. Shin, Kensuke Sugiura, Secunda W. Kariuki, David A. Cohen, Samuel P. Flashner, Andres J. Klein-Szanto, Noriyuki Nishiwaki, Dechokyab De, Neil Vasan, Joel T. Gabre, Christopher J. Lengner, Peter A. Sims, Anil K. Rustgi

    Published in The Journal of Clinical Investigation (2025-04-01)
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  9. 9

    GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells by Rafael Jesus Fernandez, Zachary JG Gardner, Katherine J Slovik, Derek C Liberti, Katrina N Estep, Wenli Yang, Qijun Chen, Garrett T Santini, Javier V Perez, Sarah Root, Ranvir Bhatia, John W Tobias, Apoorva Babu, Michael P Morley, David B Frank, Edward E Morrisey, Christopher J Lengner, F Brad Johnson

    Published in eLife (2022-05-01)
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  10. 10

    Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment by Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Justine Jou, Ian W. Folkert, Pengfei Yu, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner

    Published in Nature Communications (2023-11-01)
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  11. 11

    Cycling Stem Cells Are Radioresistant and Regenerate the Intestine by Xiaole Sheng, Ziguang Lin, Cong Lv, Chunlei Shao, Xueyun Bi, Min Deng, Jiuzhi Xu, Christian F. Guerrero-Juarez, Mengzhen Li, Xi Wu, Ran Zhao, Xu Yang, Guilin Li, Xiaowei Liu, Qingyu Wang, Qing Nie, Wei Cui, Shan Gao, Hongquan Zhang, Zhihua Liu, Yingzi Cong, Maksim V. Plikus, Christopher J. Lengner, Bogi Andersen, Fazheng Ren, Zhengquan Yu

    Published in Cell Reports (2020-07-01)
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