Search Results - Christopher M Dobson

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  1. 1

    The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases by Nunilo Cremades, Christopher M. Dobson

    Published in Neurobiology of Disease (2018-01-01)
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  2. 2

    A simple lattice model that captures protein folding, aggregation and amyloid formation. by Sanne Abeln, Michele Vendruscolo, Christopher M Dobson, Daan Frenkel

    Published in PLoS ONE (2014-01-01)
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  3. 3

    Parallel and Sequential Pathways of Molecular Recognition of a Tandem-Repeat Protein and Its Intrinsically Disordered Binding Partner by Ben M. Smith, Pamela J. E. Rowling, Christopher M. Dobson, Laura S. Itzhaki

    Published in Biomolecules (2021-06-01)
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  4. 4

    Structure of a low-population intermediate state in the release of an enzyme product by Alfonso De Simone, Francesco A Aprile, Anne Dhulesia, Christopher M Dobson, Michele Vendruscolo

    Published in eLife (2015-01-01)
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  5. 5

    The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila. by Jenna M Gregory, Teresa P Barros, Sarah Meehan, Christopher M Dobson, Leila M Luheshi

    Published in PLoS ONE (2012-01-01)
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  6. 6

    Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol by Jordan W. Oldbury, Richard A. J. Wain, Sameera Abas, Christopher M. Dobson, Srinivasan S. Iyer

    Published in Journal of Skin Cancer (2018-01-01)
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  7. 7

    Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation. by Anthony W Fitzpatrick, Tuomas P J Knowles, Christopher A Waudby, Michele Vendruscolo, Christopher M Dobson

    Published in PLoS Computational Biology (2011-10-01)
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  8. 8

    A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles by Wing K. Man, Alfonso De Simone, Joseph D. Barritt, Michele Vendruscolo, Christopher M. Dobson, Giuliana Fusco

    Published in Frontiers in Neuroscience (2020-01-01)
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  9. 9

    Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ. by David C Butler, Shubhada N Joshi, Erwin De Genst, Ankit S Baghel, Christopher M Dobson, Anne Messer

    Published in PLoS ONE (2016-01-01)
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  10. 10

    In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells. by Christopher A Waudby, Carlo Camilloni, Anthony W P Fitzpatrick, Lisa D Cabrita, Christopher M Dobson, Michele Vendruscolo, John Christodoulou

    Published in PLoS ONE (2013-01-01)
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  11. 11

    Analysis of the native structure, stability and aggregation of biotinylated human lysozyme. by Minkoo Ahn, Erwin De Genst, Gabriele S Kaminski Schierle, Miklos Erdelyi, Clemens F Kaminski, Christopher M Dobson, Janet R Kumita

    Published in PLoS ONE (2012-01-01)
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  12. 12

    The Amyloid Fibril-Forming β-Sheet Regions of Amyloid β and α-Synuclein Preferentially Interact with the Molecular Chaperone 14-3-3ζ by Danielle M. Williams, David C. Thorn, Christopher M. Dobson, Sarah Meehan, Sophie E. Jackson, Joanna M. Woodcock, John A. Carver

    Published in Molecules (2021-10-01)
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  13. 13

    Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris. by Graham Whyteside, Marcos J C Alcocer, Janet R Kumita, Christopher M Dobson, Maria Lazarou, Richard J Pleass, David B Archer

    Published in PLoS ONE (2011-01-01)
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  14. 14

    Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity. by Leila M Luheshi, Gian Gaetano Tartaglia, Ann-Christin Brorsson, Amol P Pawar, Ian E Watson, Fabrizio Chiti, Michele Vendruscolo, David A Lomas, Christopher M Dobson, Damian C Crowther

    Published in PLoS Biology (2007-10-01)
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  15. 15

    Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation. by Cintia Roodveldt, Adahir Labrador-Garrido, Elena Gonzalez-Rey, Christian C Lachaud, Tim Guilliams, Rafael Fernandez-Montesinos, Alicia Benitez-Rondan, Gema Robledo, Abdelkrim Hmadcha, Mario Delgado, Christopher M Dobson, David Pozo

    Published in PLoS ONE (2013-01-01)
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  16. 16

    An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils by Emil Dandanell Agerschou, Patrick Flagmeier, Theodora Saridaki, Céline Galvagnion, Daniel Komnig, Laetitia Heid, Vibha Prasad, Hamed Shaykhalishahi, Dieter Willbold, Christopher M Dobson, Aaron Voigt, Bjoern Falkenburger, Wolfgang Hoyer, Alexander K Buell

    Published in eLife (2019-08-01)
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  17. 17

    The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity by Catherine K. Xu, Marta Castellana-Cruz, Serene W. Chen, Zhen Du, Georg Meisl, Aviad Levin, Benedetta Mannini, Laura S. Itzhaki, Tuomas P. J. Knowles, Christopher M. Dobson, Nunilo Cremades, Janet R. Kumita

    Published in Molecules (2022-02-01)
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  18. 18

    Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. by Leila M Luheshi, Wolfgang Hoyer, Teresa Pereira de Barros, Iris van Dijk Härd, Ann-Christin Brorsson, Bertil Macao, Cecilia Persson, Damian C Crowther, David A Lomas, Stefan Ståhl, Christopher M Dobson, Torleif Härd

    Published in PLoS Biology (2010-03-01)
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  19. 19

    Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. by Kiran Yanamandra, Oleg Alexeyev, Vladimir Zamotin, Vaibhav Srivastava, Andrei Shchukarev, Ann-Christin Brorsson, Gian Gaetano Tartaglia, Thomas Vogl, Rakez Kayed, Gunnar Wingsle, Jan Olsson, Christopher M Dobson, Anders Bergh, Fredrik Elgh, Ludmilla A Morozova-Roche

    Published in PLoS ONE (2009-01-01)
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  20. 20

    Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. by Gergely Tóth, Shyra J Gardai, Wagner Zago, Carlos W Bertoncini, Nunilo Cremades, Susan L Roy, Mitali A Tambe, Jean-Christophe Rochet, Celine Galvagnion, Gaia Skibinski, Steven Finkbeiner, Michael Bova, Karin Regnstrom, San-San Chiou, Jennifer Johnston, Kari Callaway, John P Anderson, Michael F Jobling, Alexander K Buell, Ted A Yednock, Tuomas P J Knowles, Michele Vendruscolo, John Christodoulou, Christopher M Dobson, Dale Schenk, Lisa McConlogue

    Published in PLoS ONE (2014-01-01)
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