Search Results - Edwin Cuppen

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  1. 1

    Learning mutational signatures and their multidimensional genomic properties with TensorSignatures by Harald Vöhringer, Arne Van Hoeck, Edwin Cuppen, Moritz Gerstung

    Published in Nature Communications (2021-06-01)
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  2. 2

    Common anti-cancer therapies induce somatic mutations in stem cells of healthy tissue by Ewart Kuijk, Onno Kranenburg, Edwin Cuppen, Arne Van Hoeck

    Published in Nature Communications (2022-10-01)
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  3. 3

    Portrait of a cancer: mutational signature analyses for cancer diagnostics by Arne Van Hoeck, Niels H. Tjoonk, Ruben van Boxtel, Edwin Cuppen

    Published in BMC Cancer (2019-05-01)
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  4. 4

    Haplotype block structure is conserved across mammals. by Victor Guryev, Bart M G Smits, Jose van de Belt, Mark Verheul, Norbert Hubner, Edwin Cuppen

    Published in PLoS Genetics (2006-07-01)
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  5. 5

    The genome-wide mutational consequences of DNA hypomethylation by Nicolle Besselink, Janneke Keijer, Carlo Vermeulen, Sander Boymans, Jeroen de Ridder, Arne van Hoeck, Edwin Cuppen, Ewart Kuijk

    Published in Scientific Reports (2023-04-01)
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  6. 6

    A mutation in Myo15 leads to Usher-like symptoms in LEW/Ztm-ci2 rats. by Nadine Held, Bart M G Smits, Roland Gockeln, Stephanie Schubert, Heike Nave, Emily Northrup, Edwin Cuppen, Hans J Hedrich, Dirk Wedekind

    Published in PLoS ONE (2011-01-01)
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  7. 7

    Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance by Ingrid M. Ariës, Rosanna E. van den Dungen, Marco J. Koudijs, Edwin Cuppen, Emile Voest, Jan J. Molenaar, Huib N. Caron, Rob Pieters, Monique L. den Boer

    Published in Haematologica (2015-04-01)
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  8. 8

    Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications by Daniel J. Vis, Sander A. L. Palit, Marie Corradi, Edwin Cuppen, Niven Mehra, Martijn P. Lolkema, Lodewyk F. A. Wessels, Michiel S. van der Heijden, Wilbert Zwart, Andries M. Bergman

    Published in Genome Medicine (2025-03-01)
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  9. 9

    Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling by Astrid Eijkelenboom, Michal Mokry, Elzo de Wit, Lydia M Smits, Paulien E Polderman, Miranda H van Triest, Ruben van Boxtel, Almut Schulze, Wouter de Laat, Edwin Cuppen, Boudewijn M T Burgering

    Published in Molecular Systems Biology (2013-01-01)
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  10. 10

    A deep sequencing approach to uncover the miRNOME in the human heart. by Stefanos Leptidis, Hamid El Azzouzi, Sjoukje I Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J De Windt, Paula da Costa Martins

    Published in PLoS ONE (2013-01-01)
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  11. 11

    Correction: A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart. by Stefanos Leptidis, Hamid el Azzouzi, Sjoukje I. Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J. Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J. De Windt, Paula da Costa Martins

    Published in PLoS ONE (2013-01-01)
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  12. 12

    Large-Scale Identification of Coregulated Enhancer Networks in the Adult Human Brain by Marit W. Vermunt, Peter Reinink, Jeroen Korving, Ewart de Bruijn, Paul M. Creyghton, Onur Basak, Geert Geeven, Pim W. Toonen, Nico Lansu, Charles Meunier, Sebastiaan van Heesch, Hans Clevers, Wouter de Laat, Edwin Cuppen, Menno P. Creyghton

    Published in Cell Reports (2014-10-01)
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  13. 13

    Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns by Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid D. Morris, Lincoln D. Stein, PCAWG Consortium

    Published in Nature Communications (2022-12-01)
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  14. 14

    Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma by Lindsay V. M. Leek, Jessica C. L. Notohardjo, Karlijn de Joode, Eline L. Velker, John B. A. G. Haanen, Karijn P. M. Suijkerbuijk, Maureen J. B. Aarts, Jan Willem B. de Groot, Ellen Kapiteijn, Franchette W. P. J. van den Berkmortel, Hans M. Westgeest, Tanja D. de Gruijl, Valesca P. Retel, Edwin Cuppen, Astrid A. M. van der Veldt, Mariette Labots, Emile E. Voest, Joris van de Haar, Alfons J. M. van den Eertwegh

    Published in Scientific Reports (2024-05-01)
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  15. 15

    Genomic and Functional Overlap between Somatic and Germline Chromosomal Rearrangements by Sebastiaan van Heesch, Marieke Simonis, Markus J. van Roosmalen, Vamsee Pillalamarri, Harrison Brand, Ewart W. Kuijk, Kim L. de Luca, Nico Lansu, A. Koen Braat, Androniki Menelaou, Wensi Hao, Jeroen Korving, Simone Snijder, Lars T. van der Veken, Ron Hochstenbach, Alida C. Knegt, Karen Duran, Ivo Renkens, Najla Alekozai, Myrthe Jager, Sarah Vergult, Björn Menten, Ewart de Bruijn, Sander Boymans, Elly Ippel, Ellen van Binsbergen, Michael E. Talkowski, Klaske Lichtenbelt, Edwin Cuppen, Wigard P. Kloosterman

    Published in Cell Reports (2014-12-01)
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