Portrait of a cancer: mutational signature analyses for cancer diagnostics

Abstract Background In the past decade, systematic and comprehensive analyses of cancer genomes have identified cancer driver genes and revealed unprecedented insight into the molecular mechanisms underlying the initiation and progression of cancer. These studies illustrate that although every cance...

Full description

Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Arne Van Hoeck, Niels H. Tjoonk, Ruben van Boxtel, Edwin Cuppen
Format:	Article
Language:	English
Published:	BMC 2019-05-01
Subjects:	Mutational signature, Cancer diagnosis, Cancer biomarkers, Cancer genomics, Molecular medicine, Whole genome sequencing
Online Access:	http://link.springer.com/article/10.1186/s12885-019-5677-2