Search Results - Emilio Hirsch

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  1. 1

    PI3K/Akt in IPF: untangling fibrosis and charting therapies by Janki Bhatt, Janki Bhatt, Alessandra Ghigo, Alessandra Ghigo, Emilio Hirsch, Emilio Hirsch

    Published in Frontiers in Immunology (2025-03-01)
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  2. 2

    Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions by Carlotta Costa, Giulia Germena, Emilio Hirsch

    Published in The Scientific World Journal (2010-01-01)
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  3. 3

    Mechanisms of Anthracycline-Induced Cardiotoxicity: Is Mitochondrial Dysfunction the Answer? by Alessandra Murabito, Emilio Hirsch, Alessandra Ghigo

    Published in Frontiers in Cardiovascular Medicine (2020-03-01)
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  4. 4

    The turtle and the rabbit story in a modern (PI3)key by Miriam Martini, Maria Chiara De Santis, Emilio Hirsch

    Published in Molecular & Cellular Oncology (2018-01-01)
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  5. 5

    Roles of phosphatidyl inositol 3 kinase gamma (PI3Kγ) in respiratory diseases by Valentina Sala, Angela Della Sala, Alessandra Ghigo, Emilio Hirsch

    Published in Cell Stress (2021-03-01)
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  6. 6

    PI3K Signaling in Mechanisms and Treatments of Pulmonary Fibrosis Following Sepsis and Acute Lung Injury by Jean Piero Margaria, Lucia Moretta, Jose Carlos Alves-Filho, Emilio Hirsch

    Published in Biomedicines (2022-03-01)
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  7. 7

    Role of PDE4 Family in Cardiomyocyte Physiology and Heart Failure by Ivan Sherstnev, Aleksandra Judina, Giovanni Battista Luciani, Alessandra Ghigo, Emilio Hirsch, Julia Gorelik

    Published in Cells (2025-03-01)
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  8. 8

    PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth. by Michael C Schmid, Irene Franco, Sang Won Kang, Emilio Hirsch, Lawrence A Quilliam, Judith A Varner

    Published in PLoS ONE (2013-01-01)
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  9. 9

    Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia by Kirsten Bucher, Fee Schmitt, Benedikt Mothes, Carolin Blumendeller, Daniel Schäll, Roland Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer

    Published in Cell Communication and Signaling (2017-07-01)
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  10. 10

    Lack of kinase‐independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling by Ivana D'Andrea, Valentina Fardella, Stefania Fardella, Fabio Pallante, Alessandra Ghigo, Roberta Iacobucci, Angelo Maffei, Emilio Hirsch, Giuseppe Lembo, Daniela Carnevale

    Published in EMBO Molecular Medicine (2015-04-01)
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  11. 11

    PI3K as Mediator of Apoptosis and Contractile Dysfunction in TGFβ<sub>1</sub>-Stimulated Cardiomyocytes by Paulin Brosinsky, Julia Bornbaum, Björn Warga, Lisa Schulz, Klaus-Dieter Schlüter, Alessandra Ghigo, Emilio Hirsch, Rainer Schulz, Gerhild Euler, Jacqueline Heger

    Published in Biology (2021-07-01)
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  12. 12

    Genetic Deletion and Pharmacological Inhibition of PI3Kγ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease by Maria Galluzzo, Elisa Ciraolo, Monica Lucattelli, Eriola Hoxha, Martina Ulrich, Carlo Cosimo Campa, Giuseppe Lungarella, Gerd Doring, Zhe Zhou-Suckow, Marcus Mall, Emilio Hirsch, Virginia De Rose

    Published in Mediators of Inflammation (2015-01-01)
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  13. 13

    Dietary ω-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease by Brian T. Kalish, Alessandro Matte, Immacolata Andolfo, Achille Iolascon, Olga Weinberg, Alessandra Ghigo, James Cimino, Angela Siciliano, Emilio Hirsch, Enrica Federti, Mark Puder, Carlo Brugnara, Lucia De Franceschi

    Published in Haematologica (2015-07-01)
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  14. 14

    PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control. by Romy Walser, John E Burke, Elena Gogvadze, Thomas Bohnacker, Xuxiao Zhang, Daniel Hess, Peter Küenzi, Michael Leitges, Emilio Hirsch, Roger L Williams, Muriel Laffargue, Matthias P Wymann

    Published in PLoS Biology (2013-01-01)
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  15. 15

    PI3Kγ inhibition combined with DNA vaccination unleashes a B-cell-dependent antitumor immunity that hampers pancreatic cancer by Claudia Curcio, Gianluca Mucciolo, Cecilia Roux, Silvia Brugiapaglia, Alessandro Scagliotti, Giorgia Guadagnin, Laura Conti, Dario Longo, Demis Grosso, Mauro Giulio Papotti, Emilio Hirsch, Paola Cappello, Judith A. Varner, Francesco Novelli

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  16. 16

    PI3Kγ signaling controls trafficking of CD8+ T cells between lymphoid and non-lymphoid organs and drives hypertension in a murine model by Marialuisa Perrotta, Sara Perrotta, Lorenzo Carnevale, Agnese Migliaccio, Fabio Pallante, Ryszard Nosalski, Tomasz J. Guzik, Stefania Fardella, Emilio Hirsch, Valentina Fardella, Azzurra Zonfrilli, Jacopo Pacella, Matthias P. Wymann, Giuseppe Lembo, Daniela Carnevale

    Published in Nature Communications (2025-07-01)
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  17. 17

    Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure by Rima Kamel, Aurélia Bourcier, Jean Piero Margaria, Valentin Jin, Audrey Varin, Agnès Hivonnait, Françoise Mercier‐Nomé, Delphine Mika, Alessandra Ghigo, Flavien Charpentier, Vincent Algalarrondo, Emilio Hirsch, Rodolphe Fischmeister, Grégoire Vandecasteele, Jérôme Leroy

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  18. 18

    Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation by Qian Liu, Vsevolod Telezhkin, Wenkai Jiang, Yu Gu, Yan Wang, Wei Hong, Weiming Tian, Polina Yarova, Gaofeng Zhang, Simon Ming-yuen Lee, Peng Zhang, Min Zhao, Nicholas D. Allen, Emilio Hirsch, Josef Penninger, Bing Song

    Published in Cell & Bioscience (2023-01-01)
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  19. 19

    Loss of ARHGAP15 affects the directional control of migrating interneurons in the embryonic cortex and increases susceptibility to epilepsy by Carla Liaci, Mattia Camera, Valentina Zamboni, Gabriella Sarò, Alessandra Ammoni, Elena Parmigiani, Luisa Ponzoni, Enis Hidisoglu, Giuseppe Chiantia, Andrea Marcantoni, Maurizio Giustetto, Giulia Tomagra, Valentina Carabelli, Federico Torelli, Federico Torelli, Mariaelvina Sala, Yuchio Yanagawa, Kunihiko Obata, Emilio Hirsch, Giorgio R. Merlo

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  20. 20

    Correction: Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma by Cecilia Bandini, Elisabetta Mereu, Tina Paradzik, Maria Labrador, Monica Maccagno, Michela Cumerlato, Federico Oreglia, Lorenzo Prever, Veronica Manicardi, Elisa Taiana, Domenica Ronchetti, Mattia D’Agostino, Francesca Gay, Alessandra Larocca, Lenka Besse, Giorgio Roberto Merlo, Emilio Hirsch, Alessia Ciarrocchi, Giorgio Inghirami, Antonino Neri, Roberto Piva

    Published in Experimental Hematology & Oncology (2025-06-01)
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