Search Results - J Wade Harper
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p97/VCP is required for piecemeal autophagy of aggresomes by Maria Körner, Paul Müller, Hirak Das, Felix Kraus, Timo Pfeuffer, Sven Spielhaupter, Silke Oeljeklaus, Christina Schülein-Völk, J. Wade Harper, Bettina Warscheid, Alexander Buchberger
Published in Nature Communications (2025-05-01)Get full text
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Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets by Michelle E. Watts, Michelle E. Watts, Richard M. Giadone, Richard M. Giadone, Alban Ordureau, Kristina M. Holton, Kristina M. Holton, J. Wade Harper, Lee L. Rubin, Lee L. Rubin
Published in Frontiers in Cellular Neuroscience (2024-01-01)Get full text
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Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons by Tim Ahfeldt, Alban Ordureau, Christina Bell, Lily Sarrafha, Chicheng Sun, Silvia Piccinotti, Tobias Grass, Gustavo M. Parfitt, Joao A. Paulo, Fumiki Yanagawa, Takayuki Uozumi, Yasujiro Kiyota, J. Wade Harper, Lee L. Rubin
Published in Stem Cell Reports (2020-01-01)Get full text
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Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics by Hankum Park, Frances V. Hundley, Qing Yu, Katherine A. Overmyer, Dain R. Brademan, Lia Serrano, Joao A. Paulo, Julia C. Paoli, Sharan Swarup, Joshua J. Coon, Steven P. Gygi, J. Wade Harper
Published in Nature Communications (2022-10-01)Get full text
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NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms by Naiara Santana-Codina, Sebastian Gableske, Maria Quiles del Rey, Beata Małachowska, Mark P. Jedrychowski, Douglas E. Biancur, Paul J. Schmidt, Mark D. Fleming, Wojciech Fendler, J. Wade Harper, Alec C. Kimmelman, Joseph D. Mancias
Published in Haematologica (2019-07-01)Get full text
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Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases by Daniel C. Scott, Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel A. Maiwald, Kelly Churion, Amanda Nourse, Chan Lee, Joao A. Paulo, Darcie J. Miller, Stephen J. Elledge, J. Wade Harper, Gary Kleiger, Brenda A. Schulman
Published in Nature Communications (2024-11-01)Get full text
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The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis by Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo
Published in eLife (2016-02-01)Get full text
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EDF1 coordinates cellular responses to ribosome collisions by Niladri K Sinha, Alban Ordureau, Katharina Best, James A Saba, Boris Zinshteyn, Elayanambi Sundaramoorthy, Amit Fulzele, Danielle M Garshott, Timo Denk, Matthias Thoms, Joao A Paulo, J Wade Harper, Eric J Bennett, Roland Beckmann, Rachel Green
Published in eLife (2020-08-01)Get full text
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Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis by Sebastian Boland, Sharan Swarup, Yohannes A. Ambaw, Pedro C. Malia, Ruth C. Richards, Alexander W. Fischer, Shubham Singh, Geetika Aggarwal, Salvatore Spina, Alissa L. Nana, Lea T. Grinberg, William W. Seeley, Michal A. Surma, Christian Klose, Joao A. Paulo, Andrew D. Nguyen, J. Wade Harper, Tobias C. Walther, Robert V. Farese
Published in Nature Communications (2022-10-01)Get full text
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QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease by Virginia Guarani, Claude Jardel, Dominique Chrétien, Anne Lombès, Paule Bénit, Clémence Labasse, Emmanuelle Lacène, Agnès Bourillon, Apolline Imbard, Jean-François Benoist, Imen Dorboz, Mylène Gilleron, Eric S Goetzman, Pauline Gaignard, Abdelhamid Slama, Monique Elmaleh-Bergès, Norma B Romero, Pierre Rustin, Hélène Ogier de Baulny, Joao A Paulo, J Wade Harper, Manuel Schiff
Published in eLife (2016-09-01)Get full text
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Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2 by Daniel C. Scott, Suresh Dharuman, Elizabeth Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King, Rajendra Tangallapally, Chan Lee, Clifford T. Gee, Lei Yang, Yong Li, Victoria C. Loudon, Ha Won Lee, Jason Ochoada, Darcie J. Miller, Thilina Jayasinghe, Joao A. Paulo, Stephen J. Elledge, J. Wade Harper, Taosheng Chen, Richard E. Lee, Brenda A. Schulman
Published in Nature Communications (2024-10-01)Get full text
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