Search Results - Jacob D. Estes
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Editorial: Viral impact on CNS: mechanisms of immune dysfunction and cognitive decline by Thomas A. Angelovich, Thomas A. Angelovich, Thomas A. Angelovich, Sonia Mediouni, Robyn S. Klein, Jacob D. Estes, Jacob D. Estes, Bruce J. Brew, Bruce J. Brew, Melissa J. Churchill, Melissa J. Churchill, Melissa J. Churchill
Published in Frontiers in Immunology (2025-06-01)Get full text
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Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective by Malika Aid, Frank P. Dupuy, Eirini Moysi, Susan Moir, Elias K. Haddad, Jacob D. Estes, Rafick Pierre Sekaly, Constantinos Petrovas, Susan Pereira Ribeiro
Published in Frontiers in Immunology (2018-06-01)Get full text
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Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV by Sarah J. Byrnes, Janna Jamal Eddine, Jingling Zhou, Emily Chalmers, Emma Wanicek, Narin Osman, Trisha A. Jenkins, Michael Roche, Michael Roche, Bruce J. Brew, Bruce J. Brew, Jacob D. Estes, Jacob D. Estes, Thomas A. Angelovich, Thomas A. Angelovich, Thomas A. Angelovich, Melissa J. Churchill, Melissa J. Churchill, Melissa J. Churchill
Published in Frontiers in Immunology (2025-05-01)Get full text
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Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. by Haiying Li, Laura E Richert-Spuhler, Tristan I Evans, Jacqueline Gillis, Michelle Connole, Jacob D Estes, Brandon F Keele, Nichole R Klatt, R Keith Reeves
Published in PLoS Pathogens (2014-12-01)Get full text
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Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission. by Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes, Gary L Griffiths, Hisataka Kobayashi, Peter L Choyke, Jeffrey D Lifson, Brandon F Keele
Published in PLoS ONE (2014-01-01)Get full text
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Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys by Kevin D. Raehtz, Cuiling Xu, Claire Deleage, Dongzhu Ma, Benjamin B. Policicchio, Egidio Brocca-Cofano, Daniele Piccolo, Kathryn Weaver, Brandon F. Keele, Jacob D. Estes, Cristian Apetrei, Ivona Pandrea
Published in JCI Insight (2024-12-01)Get full text
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MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity. by Netanya S Utay, Annelys Roque, J Katherina Timmer, David R Morcock, Claire DeLeage, Anoma Somasunderam, Amy C Weintrob, Brian K Agan, Jacob D Estes, Nancy F Crum-Cianflone, Daniel C Douek
Published in PLoS Pathogens (2016-04-01)Get full text
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Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques. by Malika Aid, Samuel J Vidal, Cesar Piedra-Mora, Sarah Ducat, Chi N Chan, Stephen Bondoc, Alessandro Colarusso, Carly E Starke, Michael Nekorchuk, Kathleen Busman-Sahay, Jacob D Estes, Amanda J Martinot, Dan H Barouch
Published in PLoS Pathogens (2022-04-01)Get full text
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Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. by Suresh Pallikkuth, Luca Micci, Zachary S Ende, Robin I Iriele, Barbara Cervasi, Benton Lawson, Colleen S McGary, Kenneth A Rogers, James G Else, Guido Silvestri, Kirk Easley, Jacob D Estes, Francois Villinger, Savita Pahwa, Mirko Paiardini
Published in PLoS Pathogens (2013-01-01)Get full text
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African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. by Kevin D Raehtz, Fredrik Barrenäs, Cuiling Xu, Kathleen Busman-Sahay, Audrey Valentine, Lynn Law, Dongzhu Ma, Benjamin B Policicchio, Viskam Wijewardana, Egidio Brocca-Cofano, Anita Trichel, Michael Gale, Brandon F Keele, Jacob D Estes, Cristian Apetrei, Ivona Pandrea
Published in PLoS Pathogens (2020-03-01)Get full text
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IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health by Louise A. Swainson, Ashish Arunkumar Sharma, Khader Ghneim, Susan Pereira Ribeiro, Peter Wilkinson, Richard M. Dunham, Rebecca G. Albright, Samson Wong, Jacob D. Estes, Michael Piatak, Steven G. Deeks, Peter W. Hunt, Rafick-Pierre Sekaly, Joseph M. McCune
Published in JCI Insight (2022-03-01)Get full text
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Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys by Quentin Le Hingrat, Paola Sette, Cuiling Xu, Andrew R. Rahmberg, Lilas Tarnus, Haritha Annapureddy, Adam Kleinman, Egidio Brocca-Cofano, Ranjit Sivanandham, Sindhuja Sivanandham, Tianyu He, Daniel J. Capreri, Dongzhu Ma, Jacob D. Estes, Jason M. Brenchley, Cristian Apetrei, Ivona Pandrea
Published in Nature Communications (2023-02-01)Get full text
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Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants by Christopher W. Peterson, Jennifer E. Adair, Martin E. Wohlfahrt, Claire Deleage, Stefan Radtke, Blake Rust, Krystin K. Norman, Zachary K. Norgaard, Lauren E. Schefter, Gabriella M. Sghia-Hughes, Andrea Repetto, Audrey Baldessari, Robert D. Murnane, Jacob D. Estes, Hans-Peter Kiem
Published in Stem Cell Reports (2019-07-01)Get full text
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HIV transcription persists in the brain of virally suppressed people with HIV. by Janna Jamal Eddine, Thomas A Angelovich, Jingling Zhou, Sarah J Byrnes, Carolin Tumpach, Nadia Saraya, Emily Chalmers, Rory A Shepherd, Abigail Tan, Stephanie Marinis, Paul R Gorry, Jacob D Estes, Bruce J Brew, Sharon R Lewin, Sushama Telwatte, Michael Roche, Melissa J Churchill
Published in PLoS Pathogens (2024-08-01)Get full text
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Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection. by Kasha P Singh, Jennifer M Zerbato, Wei Zhao, Sabine Braat, Claire Deleage, G Surekha Tennakoon, Hugh Mason, Ashanti Dantanarayana, Ajantha Rhodes, Jake W Rhodes, Joe Torresi, Andrew N Harman, Peter A Revill, Megan Crane, Jacob D Estes, Anchalee Avihingsanon, Sharon R Lewin, Jennifer Audsley
Published in PLoS Pathogens (2020-09-01)Get full text
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Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. by Irini Sereti, Jacob D Estes, William L Thompson, David R Morcock, Margaret A Fischl, Thérèse Croughs, Stéphanie Beq, Sylvie Lafaye de Micheaux, Michael D Yao, Alexander Ober, Eleanor M P Wilson, Ven Natarajan, Hiromi Imamichi, Mohamed R Boulassel, Michael M Lederman, Jean-Pierre Routy
Published in PLoS Pathogens (2014-01-01)Get full text
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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques. by Sarah J Byrnes, Kathleen Busman-Sahay, Thomas A Angelovich, Skyler Younger, Sol Taylor-Brill, Michael Nekorchuk, Stephen Bondoc, Rachel Dannay, Margaret Terry, Catherine R Cochrane, Trisha A Jenkins, Michael Roche, Claire Deleage, Steven E Bosinger, Mirko Paiardini, Bruce J Brew, Jacob D Estes, Melissa J Churchill
Published in PLoS Pathogens (2023-03-01)Get full text
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A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals by Leslie Renee Cockerham, Steven A. Yukl, Kara Harvill, Ma Somsouk, Sunil K. Joshi, Elizabeth Sinclair, Teri Liegler, Rebecca Hoh, Sophie Lyons, Peter W. Hunt, Adam Rupert, Irini Sereti, David R. Morcock, Ajantha Rhodes, Claire Emson, Marc K. Hellerstein, Jacob D. Estes, Sharon Lewin, Steven G. Deeks, Hiroyu Hatano
Published in Pathogens and Immunity (2017-08-01)Get full text
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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. by Luca Micci, Xavier Alvarez, Robin I Iriele, Alexandra M Ortiz, Emily S Ryan, Colleen S McGary, Claire Deleage, Brigitte B McAtee, Tianyu He, Cristian Apetrei, Kirk Easley, Savita Pahwa, Ronald G Collman, Cynthia A Derdeyn, Miles P Davenport, Jacob D Estes, Guido Silvestri, Andrew A Lackner, Mirko Paiardini
Published in PLoS Pathogens (2014-10-01)Get full text
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