Search Results - James M. Cook
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Synthesis and Receptor Binding Studies of α5 GABA<sub>A</sub>R Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders by Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D. Prevot, Etienne Sibille, Jeffrey M. Witkin, James M. Cook
Published in Molecules (2023-06-01)Get full text
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12
KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy by Jodi L. Smith, Jeremy Wertz, Arnold Lippa, Xingjie Ping, Xiaoming Jin, James M. Cook, Jeffrey M. Witkin, Rok Cerne
Published in Heliyon (2024-01-01)Get full text
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13
The α6 GABA<sub>A</sub> Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome by Roberto Cadeddu, Daniel E. Knutson, Laura J. Mosher, Stefanos Loizou, Karen Odeh, Janet L. Fisher, James M. Cook, Marco Bortolato
Published in Biomolecules (2021-01-01)Get full text
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14
Zolpidem Activation of Alpha 1-Containing GABAA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons by Elena Neumann, Uwe Rudolph, Daniel E. Knutson, Guanguan Li, James M. Cook, Harald Hentschke, Bernd Antkowiak, Bernd Antkowiak, Berthold Drexler
Published in Frontiers in Pharmacology (2019-01-01)Get full text
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15
Behavioral Domain‐Specific Effects of Positive Modulation of α5 and α6 GABAA Receptors in a Rat Double‐Hit Stress Model by Đorđe Đorović, Jovana Aranđelović, Jana Ivanović, Kristina Jezdić, Bojan Batinić, Dishary Sharmin, Prithu Mondal, James M. Cook, Miroslav M. Savić
Published in Pharmacology Research & Perspectives (2026-06-01)Get full text
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16
Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor <i>N</i><sub>4</sub>-Methyltalpinine by Md Toufiqur Rahman, Veera Venkata Naga Phani Babu Tiruveedhula, Michael Rajesh Stephen, Sundari K. Rallapalli, Kamal P. Pandey, James M. Cook
Published in Molecules (2022-03-01)Get full text
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17
GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats by Barbara Kosmowska, Martyna Paleczna, Dominika Biała, Justyna Kadłuczka, Jadwiga Wardas, Jeffrey M. Witkin, James M. Cook, Dishary Sharmin, Monika Marcinkowska, Katarzyna Z. Kuter
Published in Biomolecules (2023-01-01)Get full text
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18
α4-containing GABAA receptors are required for antagonism of ethanol-induced motor incoordination and hypnosis by the imidazobenzodiazepine Ro15-4513 by Sangeetha V. Iyer, Rodrigo eBenavides, Dev eChandra, James M Cook, Sundari eRallapalli, Harry L. June, Gregg E Homanics, Gregg E Homanics
Published in Frontiers in Pharmacology (2011-04-01)Get full text
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Therapeutic effects of KRM-II-81, positive allosteric modulator for α2/3 subunit containing GABAA receptors, in a mouse model of Dravet syndrome by Sachiko Nakakubo, Yasuyoshi Hiramatsu, Takeru Goto, Syuhei Kimura, Masashi Narugami, Midori Nakajima, Yuki Ueda, Hideaki Shiraishi, Atsushi Manabe, Dishary Sharmin, James M. Cook, Kiyoshi Egawa
Published in Frontiers in Pharmacology (2023-10-01)Get full text
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20
Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92 by William R. Schwan, Jill M. Kolesar, M. Shahjahan Kabir, Edmund J. Elder, Jeffrey B. Williams, Rachel Minerath, James M. Cook, Christopher M. Witzigmann, Aaron Monte, Tricia Flaherty
Published in Antibiotics (2015-11-01)Get full text
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