Search Results - Louis Scampavia
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High throughput screening for SARS-CoV-2 inhibitors targeting 5 helix bundle by Emery Smith, Qibin Geng, Justin Shumate, Yuka Otsuka, Louis Scampavia, Thomas D. Bannister, Timothy P. Spicer
Published in SLAS Discovery (2025-09-01)Get full text
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Cell based high-throughput screening for small molecule inhibitors of ATE1 by Claudia McCown, Evan A. Ambrose, Devang M. Patel, Hassan Al-Ali, Louis Scampavia, Fangliang Zhang, Timothy P. Spicer
Published in SLAS Discovery (2025-09-01)Get full text
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Protocol for kinetic mode potassium channel assays on common plate readers and microscopes by Emery Smith, Louise Dickson, Philip Pickford, Anna Rowland, Justin Shumate, Katherine Perez, Louis Scampavia, Derek Hernandez, Timothy P. Spicer
Published in SLAS Discovery (2024-04-01)Get full text
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Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism by Shurong Hou, Zhenzhen Li, Xiaoling Chen, Wenxin Wang, Ting Duan, Louis Scampavia, Yaxia Yuan, Timothy P. Spicer, Xiabin Chen, Tian Xie
Published in Signal Transduction and Targeted Therapy (2023-02-01)Get full text
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Simultaneous screening for selective SARS-CoV-2, Lassa, and Machupo virus entry inhibitors by Yuka Otsuka, Lizhou Zhang, Huihui Mou, Justin Shumate, Claire E. Kitzmiller, Louis Scampavia, Thomas D. Bannister, Michael Farzan, Hyeryun Choe, Timothy P. Spicer
Published in SLAS Discovery (2024-09-01)Get full text
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A high-throughput cell-based screening method for Zika virus protease inhibitor discovery by Paulina Duhita Anindita, Yuka Otsuka, Simon Lattmann, Khac Huy Ngo, Chong Wai Liew, CongBao Kang, Reuben S. Harris, Louis Scampavia, Timothy P. Spicer, Dahai Luo
Published in SLAS Discovery (2024-07-01)Get full text
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Homeostatic scaling of dynorphin signaling by a non-canonical opioid receptor by Xiaona Li, Nathan D. Winters, Shubhi Pandey, Colten Lankford, Hannah M. Stoveken, Emery Smith, Chu-Ting Chang, Stefano Zucca, Louis Scampavia, Timothy Spicer, Kirill A. Martemyanov
Published in Nature Communications (2025-07-01)Get full text
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High throughput screening for SARS-CoV-2 helicase inhibitors by Yuka Otsuka, Eunjung Kim, Austin Krueger, Justin Shumate, Chao Wang, Bilel Bdiri, Sultan Ullah, HaJeung Park, Louis Scampavia, Thomas D. Bannister, Donghoon Chung, Timothy P. Spicer
Published in SLAS Discovery (2024-09-01)Get full text
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Hyperphosphorylated tau-based Alzheimer’s Disease drug discovery: Identification of inhibitors of tau aggregation and cytotoxicity by Hsiao-Tien Hagar, Virneliz Fernandez-Vega, Kuang-Wei Wang, Luis M. Ortiz Jordan, Justin Shumate, Louis Scampavia, April Sweet Tapayan, Hien M Nguyen, Timothy P. Spicer, Min-Hao Kuo
Published in SLAS Discovery (2025-06-01)Get full text
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A new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer by EunJung Lee, Suyakarn Archasappawat, Keely Ji, Jocelyn Pena, Virneliz Fernandez-Vega, Ritika Gangaraju, Nitin Sai Beesabathuni, Martin Jean Kim, Qi Tian, Priya S. Shah, Louis Scampavia, Timothy P. Spicer, Chang-Il Hwang
Published in Cell Death and Disease (2023-09-01)Get full text
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High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2 by Emery Smith, Meredith E. Davis-Gardner, Ruben D. Garcia-Ordonez, Tu-Trinh Nguyen, Mitchell Hull, Emily Chen, Xuerong Yu, Thomas D. Bannister, Pierre Baillargeon, Louis Scampavia, Patrick Griffin, Michael Farzan, Timothy P. Spicer
Published in SLAS Discovery (2023-04-01)Get full text
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Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation by Lars Plate, Christina B Cooley, John J Chen, Ryan J Paxman, Ciara M Gallagher, Franck Madoux, Joseph C Genereux, Wesley Dobbs, Dan Garza, Timothy P Spicer, Louis Scampavia, Steven J Brown, Hugh Rosen, Evan T Powers, Peter Walter, Peter Hodder, R Luke Wiseman, Jeffery W Kelly
Published in eLife (2016-07-01)Get full text
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SARS-CoV-2 Mpro inhibitor identification using a cellular gain-of-signal assay for high-throughput screening by Renee Delgado, Jyoti Vishwakarma, Seyed Arad Moghadasi, Yuka Otsuka, Justin Shumate, Ashley Cuell, Megan Tansiongco, Christina B. Cooley, Yanjun Chen, Agnieszka Dabrowska, Rahul Basu, Paulina Duhita Anindita, Dahai Luo, Peter I. Dosa, Daniel A. Harki, Thomas Bannister, Louis Scampavia, Timothy P. Spicer, Reuben S. Harris
Published in SLAS Discovery (2024-09-01)Get full text
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