檢索結果 - Robert H Mach

67 Lipid metabolism and synthesis pathway analysis of Sigma-2 Receptor/TMEM97 in breast cancer cells 由 Aladdin Riad, David Mankof, Robert H. Mach

獲取全文

Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development 由 Chia-Ju Hsieh, Sam Giannakoulias, E. James Petersson, Robert H. Mach

獲取全文

A nanoluciferase complementation-based assay for monitoring β-arrestin2 recruitment to the dopamine D3 receptor 由 Viktor Burström, Kuiying Xu, Emilio Garro-Martínez, Robert H. Mach, Kristoffer Sahlholm, Nibal Betari

獲取全文

Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imagin... 由 Devika P Bagchi, Lihai Yu, Joel S Perlmutter, Jinbin Xu, Robert H Mach, Zhude Tu, Paul T Kotzbauer

獲取全文

Design and Synthesis of D₃R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies 由 Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R. Luedtke, Robert H. Mach

獲取全文

Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods 由 Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R. Luedtke, Robert H. Mach

獲取全文

In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor 由 Ji Youn Lee, Ho Young Kim, Paul Martorano, Aladdin Riad, Michelle Taylor, Robert R. Luedtke, Robert H. Mach

獲取全文

Characterization of Sigma-2 Receptor—Specific Binding Sites Using [³H]DTG and [¹²⁵I]RHM-4 由 Chi-Chang Weng, Aladdin Riad, Brian P. Lieberman, Kuiying Xu, Xin Peng, John L. Mikitsh, Robert H. Mach

獲取全文

Evaluation of Substituted <i>N</i>-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands 由 Boeun Lee, Michelle Taylor, Suzy A. Griffin, Tamara McInnis, Nathalie Sumien, Robert H. Mach, Robert R. Luedtke

獲取全文

Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue 由 Jennifer Y. O’Shea, Dhruva D. Dhavale, Helen Hwang, Zachary Smith, Thomas J. A. Graham, Robert H. Mach, Paul T. Kotzbauer

獲取全文

[¹⁸F]NOS PET Brain Imaging Suggests Elevated Neuroinflammation in Idiopathic Parkinson’s Disease 由 Robert K. Doot, Anthony J. Young, Ilya M. Nasrallah, Reagan R. Wetherill, Andrew Siderowf, Robert H. Mach, Jacob G. Dubroff

獲取全文

Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer 由 Chi-Chang Weng, Chao-Chih Chiang, Yi-Hsiu Chung, Yi-Pei Ho, Yu-Chuan Chang, Ing-Tsung Hsiao, Robert H. Mach

獲取全文

Click Synthesis and Biologic Evaluation of ()- and ()-2-Amino-3-[1-(2-[F]Fluoroethyl)-1-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography 由 Jonathan McConathy, Dong Zhou, Stephany E. Shockley, Lynne A. Jones, Elizabeth A. Griffin, Hsiaoju Lee, Susan J. Adams, Robert H. Mach

獲取全文

Characterization and Evaluation of Two Novel Fluorescent Sigma-2 Receptor Ligands as Proliferation Probes 由 Chenbo Zeng, Suwanna Vangveravong, Lynne A. Jones, Krzysztof Hyrc, Katherine C. Chang, Jinbin Xu, Justin M. Rothfuss, Mark P. Goldberg, Richard S. Hotchkiss, Robert H. Mach

獲取全文

[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice 由 Chia-Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan Gallagher, Kuiying Xu, Hsiaoju Lee, Shihong Li, Meagan J. McManus, Robert H. Mach

獲取全文

PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients Enable Ex-Vivo Screening of Tumor Response 由 Aladdin Riad, Sarah B. Gitto, Hwan Lee, Harrison D. Winters, Paul M. Martorano, Chia-Ju Hsieh, Kuiying Xu, Dalia K. Omran, Daniel J. Powell, Robert H. Mach, Mehran Makvandi

獲取全文

Pilot Study of [¹¹C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer 由 Chia-Ju Hsieh, Dinahlee Saturnino Guarino, Anthony J. Young, Andrew D. Siderowf, Ilya Nasrallah, Alexander Schmitz, Carol Garcia, Ho Young Kim, Erin K. Schubert, Hsiaoju Lee, Joel S. Perlmutter, Robert H. Mach

獲取全文

Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1. 由 Kooresh I Shoghi, Jinbin Xu, Yi Su, June He, Douglas Rowland, Ying Yan, Joel R Garbow, Zhude Tu, Lynne A Jones, Ryuji Higashikubo, Kenneth T Wheeler, Ronald A Lubet, Robert H Mach, Ming You

獲取全文

Monitoring mRNA vaccine antigen expression in vivo using PET/CT 由 Gabrielle S. Blizard, Garima Dwivedi, Yi-Gen Pan, Catherine Hou, Jean M. Etersque, Hooda Said, Anik Chevrier, Marc Lavertu, Houping Ni, Benjamin Davis, Ying Tam, Quy Cao, Robert H. Mach, Drew Weissman, Mohamad-Gabriel Alameh, Mark A. Sellmyer

獲取全文

PET Imaging with [¹⁸F]ROStrace Detects Oxidative Stress and Predicts Parkinson’s Disease Progression in Mice 由 Yi Zhu, Neha Kohli, Anthony Young, Malkah Sheldon, Jani Coni, Meera Rajasekaran, Lozen Robinson, Rea Chroneos, Shaipreeah Riley, Joseph W. Guarnieri, Joshua Jose, Nisha Patel, Douglas C. Wallace, Shihong Li, Hsiaoju Lee, Robert H. Mach, Meagan J. McManus

獲取全文