Search Results - Shengyong Yang
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Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer by Wen Peng, Huaqing Zhang, Shisheng Tan, Yan Li, Yang Zhou, Liang Wang, Chunqi Liu, Qiu Li, Xiaobo Cen, Shengyong Yang, Yinglan Zhao
Published in Therapeutic Advances in Medical Oncology (2020-07-01)Get full text
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Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery by Xiaoning Qi, Lianhe Zhao, Chenyu Tian, Yueyue Li, Zhen-Lin Chen, Peipei Huo, Runsheng Chen, Xiaodong Liu, Baoping Wan, Shengyong Yang, Yi Zhao
Published in Nature Communications (2024-10-01)Get full text
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Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway by Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang
Published in Cells (2022-12-01)Get full text
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Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7 by Xinyi Zhou, Xiaoyu Yang, Shenzhen Huang, Guifeng Lin, Kexin Lei, Qian Wang, Weimin Lin, Hanwen Li, Xingying Qi, Dutmanee Seriwatanachai, Shengyong Yang, Bin Shao, Quan Yuan
Published in Advanced Science (2024-07-01)Get full text
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Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor by Yueshan Li, Liting Zhang, Yifei Wang, Jun Zou, Ruicheng Yang, Xinling Luo, Chengyong Wu, Wei Yang, Chenyu Tian, Haixing Xu, Falu Wang, Xin Yang, Linli Li, Shengyong Yang
Published in Nature Communications (2022-11-01)Get full text
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Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells by Jun Luo, Yoshinobu Odaka, Zhu Huang, Bing Cheng, Wang Liu, Lin Li, Chaowei Shang, Chao Zhang, Yang Wu, Yan Luo, Shengyong Yang, Peter J. Houghton, Xiaofeng Guo, Shile Huang
Published in Cells (2021-06-01)Get full text
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Non-classical ferroptosis inhibition by a small molecule targeting PHB2 by Wei Yang, Bo Mu, Jing You, Chenyu Tian, Huachao Bin, Zhiqiang Xu, Liting Zhang, Ronggang Ma, Ming Wu, Guo Zhang, Chong Huang, Linli Li, Zhenhua Shao, Lunzhi Dai, Laurent Désaubry, Shengyong Yang
Published in Nature Communications (2022-12-01)Get full text
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TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways by Wenzhi Shen, Renle Du, Jun Li, Xiaohe Luo, Shuangtao Zhao, Antao Chang, Wei Zhou, Ruifang Gao, Dehong Luo, Juan Wang, Na Hao, Yanhua Liu, Yanan Chen, Yunping Luo, Peiqing Sun, Shengyong Yang, Na Luo, Rong Xiang
Published in Signal Transduction and Targeted Therapy (2016-07-01)Get full text
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Correction to: TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways by Wenzhi Shen, Renle Du, Jun Li, Xiaohe Luo, Shuangtao Zhao, Antao Chang, Wei Zhou, Ruifang Gao, Dehong Luo, Juan Wang, Na Hao, Yanhua Liu, Yanan Chen, Yunping Luo, Peiqing Sun, Shengyong Yang, Na Luo, Rong Xiang
Published in Signal Transduction and Targeted Therapy (2025-03-01)Get full text
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Structural and Functional Insights into an Archaeal Lipid Synthase by Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng
Published in Cell Reports (2020-10-01)Get full text
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A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants by Chong Huang, Huiping Shuai, Jingxin Qiao, Yuxin Hou, Rui Zeng, Anjie Xia, Lingwan Xie, Zhen Fang, Yueyue Li, Chaemin Yoon, Qiao Huang, Bingjie Hu, Jing You, Baoxue Quan, Xiu Zhao, Nihong Guo, Shiyu Zhang, Ronggang Ma, Jiahao Zhang, Yifei Wang, Ruicheng Yang, Shanshan Zhang, Jinshan Nan, Haixing Xu, Falu Wang, Jian Lei, Hin Chu, Shengyong Yang
Published in Signal Transduction and Targeted Therapy (2023-03-01)Get full text
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Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51 by Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao
Published in Nature Communications (2023-11-01)Get full text
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An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo by Huiping Shuai, Jingxin Qiao, Chaemin Yoon, Guo Zhang, Yuxin Hou, Xiaoyan Xia, Lei Wang, Xinyue Deng, Yifei Wang, Qingquan Li, Lianzhao Du, Yuanchen Liu, Minmin Zhou, Hoi Ting Wong, Jiaheng Hu, Huan Liu, Bingjie Hu, Dong Wang, Jingyi Su, Yuying Pan, Yongtao Ye, Yan Chen, Zhen Fang, Ziyi Xia, Yue Chai, Jialu Shi, Yang Wang, Tianrenzheng Zhu, Honglei Zhang, Shuofeng Yuan, Jie Zhou, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Chunfu Xu, Jian Lei, Shengyong Yang, Hin Chu
Published in Nature Communications (2025-07-01)Get full text
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EZH2 loss promotes gastric squamous cell carcinoma by Mengsha Zhang, Ailing Zhong, Hongyu Liu, Lei Zhao, Yingjie Wang, Zhenghao Lu, Lanxin Zhang, Xiangyu Pan, Zuoyu Liang, Limin Gao, Xuelan Chen, Jian Wang, Siqi Dai, Xudong Wan, Manli Wang, Jingyao Chen, Jiajia Du, Shuang Chen, Tingfa Peng, Jingyang Cai, Liuxiang Chen, Yang Yang, Chaoxin Xiao, Menglin Yao, Jing Xu, Runkuan Qin, Chan Yang, Baohong Wu, Qi Zhang, Shengzhuo Liu, Chengjian Zhao, Hongxin Deng, Yuan Wang, Lu Chen, Jiankun Hu, Bing Hu, Shengyong Yang, Feifei Na, Linjie Guo, Yu Liu, Chong Chen
Published in Nature Communications (2025-07-01)Get full text
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