Search Results - Taha Merghoub

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  1. 1

    525 Investigating dynamic IDO-Kyn-AhR pathway-induced tumor immunosuppression using imaging modality to optimize AhR therapeutic intervention by Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Inna Serganova, Jonathan F Khan, Mamadou A Bah

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  2. 2

    Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant by Ning Yang, Aitor Garcia, Cindy Meyer, Thomas Tuschl, Taha Merghoub, Jedd D. Wolchok, Liang Deng

    Published in npj Vaccines (2022-10-01)
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  3. 3

    968 PD-1hiFoxp3-CD4+ tumor-infiltrating T-cell lineage commitment impacts the immunotherapy outcome by Jedd D Wolchok, Taha Merghoub, Roberta Zappasodi, Sara Schad, Benjamin Greenbaum, Levi Mark Mangarin, Stephen Martis, Andrea Orlando

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  4. 4

    An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity by Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain

    Published in Molecular Therapy: Oncolytics (2016-01-01)
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  5. 5

    Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model by Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Jedd D. Wolchok, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Taha Merghoub, Jonathan A. Coleman, Jonathan A. Coleman

    Published in Frontiers in Oncology (2024-06-01)
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  6. 6

    789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model by Alan N Houghton, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn, Linda Hamadene, Yacine Marouf, Allison B Warner, Mariam M George, Nicholas J Ceglia

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  7. 7

    1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade by Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Svena Verma, Inna Serganova, Lauren Dong, Levi Mark Mangarin, Yacine Marouf, Jonathan F Khan

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  8. 8

    Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway. by Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng

    Published in PLoS Pathogens (2014-04-01)
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  9. 9

    Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer by Souhil Lebdai, Mathieu Gigoux, Ricardo Alvim, Alexander Somma, Karan Nagar, Abdel Rahmene Azzouzi, Olivier Cussenot, Taha Merghoub, Jedd D. Wolchok, Avigdor Scherz, Kwanghee Kim, Jonathan Coleman

    Published in OncoImmunology (2019-06-01)
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  10. 10

    Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer by Aditi Gupta, Sadna Budhu, Kelly Fitzgerald, Rachel Giese, Adam O. Michel, Aliya Holland, Luis Felipe Campesato, Jacques van Snick, Catherine Uyttenhove, Gerd Ritter, Jedd D. Wolchok, Taha Merghoub

    Published in Communications Biology (2021-11-01)
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  11. 11

    Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope. by David A Schaer, Yongbiao Li, Taha Merghoub, Gabrielle A Rizzuto, Amos Shemesh, Adam D Cohen, Yanyun Li, Francesca Avogadri, Ricardo Toledo-Crow, Alan N Houghton, Jedd D Wolchok

    Published in PLoS ONE (2011-01-01)
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  12. 12

    Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models by Svena Verma, Sadna Budhu, Inna Serganova, Lauren Dong, Levi M. Mangarin, Jonathan F. Khan, Mamadou A. Bah, Anais Assouvie, Yacine Marouf, Isabell Schulze, Roberta Zappasodi, Jedd D. Wolchok, Taha Merghoub

    Published in The Journal of Clinical Investigation (2024-09-01)
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  13. 13

    327 Development and validation of a neoantigen-specific T cell gene signature to identify antitumor T cells in lung cancer and melanoma by Jiajia Zhang, Patrick Forde, Taha Merghoub, Julie Brahmer, Matthew Hellmann, Kristen Marrone, Janis Taube, Boyang Zhang, Hongkai Ji, Zhicheng Ji, Justina Caushi, Andrew Pardoll, Kellie Smith, Giacomo Oliveira, Srinivasan Yegnasubramanian, Catherine Wu

    Published in Journal for ImmunoTherapy of Cancer (2021-11-01)
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  14. 14

    Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. by Adam D Cohen, David A Schaer, Cailian Liu, Yanyun Li, Daniel Hirschhorn-Cymmerman, Soo Chong Kim, Adi Diab, Gabrielle Rizzuto, Fei Duan, Miguel A Perales, Taha Merghoub, Alan N Houghton, Jedd D Wolchok

    Published in PLoS ONE (2010-05-01)
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  15. 15

    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer by Hyejin Choi, Jiehui Deng, Shuai Li, Tarik Silk, Lauren Dong, Elliott J. Brea, Sean Houghton, David Redmond, Hong Zhong, Jonathan Boiarsky, Esra A. Akbay, Paul D. Smith, Taha Merghoub, Kwok-Kin Wong, Jedd D. Wolchok

    Published in Cell Reports (2019-04-01)
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  16. 16

    Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma by Sadna Budhu, Rachel Giese, Aditi Gupta, Kelly Fitzgerald, Roberta Zappasodi, Sara Schad, Daniel Hirschhorn, Luis Felipe Campesato, Olivier De Henau, Mathieu Gigoux, Cailian Liu, Gregory Mazo, Liang Deng, Christopher A. Barker, Jedd D. Wolchok, Taha Merghoub

    Published in Cell Reports (2021-01-01)
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  17. 17

    Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer by Elizabeth Comen, Sadna Budhu, Yuval Elhanati, David Page, Teresa Rasalan-Ho, Erika Ritter, Phillip Wong, George Plitas, Sujata Patil, Edi Brogi, Maxine Jochelson, Yolanda Bryce, Stephen B. Solomon, Larry Norton, Taha Merghoub, Heather L. McArthur

    Published in iScience (2024-02-01)
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  18. 18

    TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models by Christopher S. Hackett, Daniel Hirschhorn, Meixian S. Tang, Terence J. Purdon, Yacine Marouf, Alessandra Piersigilli, Narasimhan P. Agaram, Cailian Liu, Sara E. Schad, Elisa de Stanchina, Sarwish Rafiq, Sebastien Monette, Jedd D. Wolchok, Taha Merghoub, Renier J. Brentjens

    Published in Molecular Therapy: Oncology (2024-09-01)
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  19. 19

    Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/− trastuzumab in patients with breast cancer brain metastases by David B. Page, Kathryn Beal, Stefanie N. Linch, Kateri J. Spinelli, Micaela Rodine, Darragh Halpenny, Shanu Modi, Sujata Patil, Robert J. Young, Thomas Kaley, Taha Merghoub, David Redmond, Phillip Wong, Christopher A. Barker, Adi Diab, Larry Norton, Heather L. McArthur

    Published in npj Breast Cancer (2022-04-01)
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  20. 20

    FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer by Yifan Tai, Angela Chow, Seoyoung Han, Courtney Coker, Wanchao Ma, Yifan Gu, Valeria Estrada Navarro, Manoj Kandpal, Hanina Hibshoosh, Kevin Kalinsky, Katia Manova-Todorova, Anton Safonov, Elaine M Walsh, Mark Robson, Larry Norton, Richard Baer, Taha Merghoub, Anup K Biswas, Swarnali Acharyya

    Published in EMBO Molecular Medicine (2024-07-01)
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