Search Results - Udo Oppermann

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  1. 1

    Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1 by Miriam R. B. Porzberg, Laust Moesgaard, Catrine Johansson, Udo Oppermann, Jacob Kongsted, Jasmin Mecinović

    Published in Molecules (2022-02-01)
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  2. 2

    HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta by Alison Dickson, Eylan Yutuc, Catherine A. Thornton, James E. Dunford, Udo Oppermann, Yuqin Wang, William J. Griffiths

    Published in Open Biology (2023-05-01)
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  3. 3

    Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia by Sachith Mettananda, Christopher A. Fisher, Jackie A. Sloane-Stanley, Stephen Taylor, Udo Oppermann, Richard J. Gibbons, Douglas R. Higgs

    Published in Haematologica (2017-03-01)
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  4. 4

    Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function by Shonagh Munro, Edward S. Hookway, Melanie Floderer, Simon M. Carr, Rebecca Konietzny, Benedikt M. Kessler, Udo Oppermann, Nicholas B. La Thangue

    Published in Cell Reports (2017-06-01)
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  5. 5

    KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics by Mai Abdel Mouti, Siwei Deng, Martin Pook, Jessica Malzahn, Aniko Rendek, Stefania Militi, Reshma Nibhani, Zahir Soonawalla, Udo Oppermann, Chang-il Hwang, Siim Pauklin

    Published in Nature Communications (2023-09-01)
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  6. 6

    The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms by Chao-Hui Chang, Feng Liu, Stefania Militi, Svenja Hester, Reshma Nibhani, Siwei Deng, James Dunford, Aniko Rendek, Zahir Soonawalla, Roman Fischer, Udo Oppermann, Siim Pauklin

    Published in Nature Communications (2024-04-01)
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  7. 7

    Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences by Jianfeng Sun, Martin Philpott, Danson Loi, Gabriela Hoffman, Jonathan Robson, Neelam Mehta, Eleanor Calcutt, Vicki Gamble, Tom Brown, Tom Brown, Udo Oppermann, Adam P. Cribbs

    Published in Communications Biology (2025-01-01)
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  8. 8

    High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. by Frank H Niesen, Lena Schultz, Ajit Jadhav, Chitra Bhatia, Kunde Guo, David J Maloney, Ewa S Pilka, Minghua Wang, Udo Oppermann, Tom D Heightman, Anton Simeonov

    Published in PLoS ONE (2010-11-01)
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  9. 9

    PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1-OVEREXPRESSING AML by Simge Kelekci, Anna Riedel, Dieter Weichenhan, Ashish Goyal, Katherine Kelly, Marion Baehr, Birgitta Michels, Cindy Koerner, Irene Orzella, James Dunford, Pavlo Lutsik, Stefan Wiemann, Udo Oppermann, Christoph Plass

    Published in HemaSphere (2023-08-01)
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  10. 10

    PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo by Elizabeth J. Brown, Leire Balaguer-Lluna, Adam P. Cribbs, Martin Philpott, Leticia Campo, Molly Browne, Jong Fu Wong, Udo Oppermann, Ángel M. Carcaboso, Alex N. Bullock, Gillian Farnie

    Published in Scientific Reports (2024-01-01)
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  11. 11

    Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer by Ozlem Yedier-Bayram, Ahmet Cingöz, Ebru Yilmaz, Ali Cenk Aksu, Beril Esin, Nareg Degirmenci, Ayse Derya Cavga, Beyza Dedeoğlu, Buse Cevatemre, Hamzah Syed, Martin Philpott, Adam P. Cribbs, Udo Oppermann, Nathan A. Lack, Ceyda Acilan, Tamer T. Onder, Tugba Bagci-Onder

    Published in Experimental and Molecular Medicine (2025-06-01)
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  12. 12

    Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. by Oliver N F King, Xuan Shirley Li, Masaaki Sakurai, Akane Kawamura, Nathan R Rose, Stanley S Ng, Amy M Quinn, Ganesha Rai, Bryan T Mott, Paul Beswick, Robert J Klose, Udo Oppermann, Ajit Jadhav, Tom D Heightman, David J Maloney, Christopher J Schofield, Anton Simeonov

    Published in PLoS ONE (2010-11-01)
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  13. 13

    Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance by Mark A. Tye, N. Connor Payne, Catrine Johansson, Kritika Singh, Sofia A. Santos, Lọla Fagbami, Akansha Pant, Kayla Sylvester, Madeline R. Luth, Sofia Marques, Malcolm Whitman, Maria M. Mota, Elizabeth A. Winzeler, Amanda K. Lukens, Emily R. Derbyshire, Udo Oppermann, Dyann F. Wirth, Ralph Mazitschek

    Published in Nature Communications (2022-08-01)
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  14. 14

    Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma by Gaurav Agarwal, Sally Moore, Ross Sadler, Sherin Varghese, Alison Turner, Lucia Y Chen, Jemma Larham, Nathanael Gray, Oluremi Carty, Joe Barrett, Constantinos Koshiaris, Jaimal Kothari, Stella Bowcock, Udo Oppermann, Vicky Gamble, Gordon Cook, Chara Kyriakou, Mark Drayson, Supratik Basu, Sarah McDonald, Shelagh McKinley, Sarah Gooding, Muhammad K Javaid, Karthik Ramasamy

    Published in Haematologica (2024-01-01)
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  15. 15

    Belantamab Mafodotin Monotherapy for Multiply‐Relapsed Myeloma: A Retrospective Study From the United Kingdom and the Republic of Ireland by Edmund C. R. Watson, Faouzi Djebbari, Fotios Panitsas, Grant Vallance, Samir Asher, Malahat Saeed, Mairi Walker, Matthew Powell, Alexandros Rampotas, Heather Leary, Akhil Khera, Angharad Atkinson, Ni Ni Aung, Gillian Brearton, Joseph Froggatt, Ezzat El Hassadi, Ellen Gokkel, Sarah Lawless, Beena Salhan, Salim Shafeek, Anand Lokare, Carol Stirling, Udo Oppermann, Richard Soutar, Rakesh Popat, Charalampia Kyriakou, Karthik Ramasamy

    Published in eJHaem (2025-06-01)
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  16. 16

    A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding by Chen-Yi Wang, Martin Philpott, Darragh P O’Brien, Anne Ndungu, Jessica Malzahn, Marina Maritati, Neelam Mehta, Vicki Gamble, Beatriz Martinez-Burgo, Sarah Bonham, Roman Fischer, Kurtis Garbutt, Christian M. Becker, Sanjiv Manek, Adrian L. Harris, Frank Sacher, Maik Obendorf, Nicole Schmidt, Jörg Müller, Thomas M. Zollner, Krina T. Zondervan, Benedikt M. Kessler, Udo Oppermann, Adam P. Cribbs

    Published in Communications Medicine (2025-07-01)
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  17. 17

    Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma by Keiji Kurata, Anna-James Bott, Mark A. Tye, Leona Yamamoto, Mehmet K. Samur, Yu-Tzu Tai, James Dunford, Catrine Johansson, Filiz Senbabaoglu, Martin Philpott, Charlotte Palmer, Karthik Ramasamy, Sarah Gooding, Mihaela Smilova, Giorgia Gaeta, Manman Guo, John C. Christianson, N. Connor Payne, Kritika Singh, Kubra Karagoz, Matthew E. Stokes, Maria Ortiz, Patrick Hagner, Anjan Thakurta, Adam Cribbs, Ralph Mazitschek, Teru Hideshima, Kenneth C. Anderson, Udo Oppermann

    Published in Blood Cancer Journal (2023-01-01)
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  18. 18

    The human milk oligosaccharide 3′sialyllactose reduces low-grade inflammation and atherosclerosis development in mice by Ariane R. Pessentheiner, Nathanael J. Spann, Chloe A. Autran, Tae Gyu Oh, Kaare V. Grunddal, Joanna K.C. Coker, Chelsea D. Painter, Bastian Ramms, Austin W.T. Chiang, Chen-Yi Wang, Jason Hsiao, Yiwen Wang, Anthony Quach, Laela M. Booshehri, Alexandra Hammond, Chiara Tognaccini, Joanna Latasiewicz, Lisa Willemsen, Karsten Zengler, Menno P.J. de Winther, Hal M. Hoffman, Martin Philpott, Adam P. Cribbs, Udo Oppermann, Nathan E. Lewis, Joseph L. Witztum, Ruth Yu, Annette R. Atkins, Michael Downes, Ron M. Evans, Christopher K. Glass, Lars Bode, Philip L.S.M. Gordts

    Published in JCI Insight (2024-11-01)
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