Use of regulatory cells for achieving functional tolerance of pig heart xenotransplants in humans: a literature review

Xenotransplantation of pig hearts may help address the current human shortage of human donors once rejection is controlled. One innovative approach to combat rejection in humans is the use of regulatory cell (RC) therapy. The term RC refers to all cell populations that share immunosuppressive functi...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Author:	Gheorghe Traian Braileanu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-11-01
Subjects:	pig heart xenotransplantation regulatory cells therapy adoptive cell transfer xenotransplant tolerance CAR transformed regulatory cells human recipients
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1648926/full