Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection

Introduction: Conventional biopsy, based on extraction from a tumor of a solid tissue specimen requiring needles, endoscopic devices, excision or surgery, is at risk of infection, internal bleeding or prolonged recovery. A non-invasive liquid biopsy is one of the greatest axiomatic consequences of t...

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Bibliographic Details

Published in:	Journal of Advanced Research
Main Authors:	Samla Gauri Balakrishnan, Mohd Ridzuan Ahmad, Seyed Saeid Rahimian Koloor, Michal Petrů
Format:	Article
Language:	English
Published:	Elsevier 2021-11-01
Subjects:	Circulating tumor DNA (ctDNA) detection Cancer biomarker Liquid biopsy Magnetic manipulation COMSOL Multiphysics Simulation study
Online Access:	http://www.sciencedirect.com/science/article/pii/S2090123221000369