FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1

Abstract Colorectal cancer (CRC) ranks as the second most lethal cancer worldwide because of its high rate of metastasis, and approximately 20% of CRC patients have metastases at initial diagnosis. Metabolic reprogramming, a hallmark of cancer cells, has been implicated in the process of metastasis....

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Chenfei Dong, Yue Zhang, Jiayue Zeng, Suli Chong, Yang Liu, Ziming Bian, Sairong Fan, Xiaoming Chen
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Online Access:	https://doi.org/10.1038/s42003-024-06993-x