Defining the Protein Phosphatase 2A (PP2A) Subcomplexes That Regulate FoxO Transcription Factor Localization

The family of forkhead box O (FoxO) transcription factors regulate cellular processes involved in glucose metabolism, stress resistance, DNA damage repair, and tumor suppression. FoxO transactivation activity is tightly regulated by a complex network of signaling pathways and post-translational modi...

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Bibliographic Details
Published in:Cells
Main Authors: Adeline M. Luperchio, Daniel J. Salamango
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Subjects:
AKT
FoxO
PI3K
PP2A
subcellular localization
transcription factor
Online Access:https://www.mdpi.com/2073-4409/14/5/342

Internet

https://www.mdpi.com/2073-4409/14/5/342

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