Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation

Abstract Endosomal retrieval and recycling of integral cargo proteins is essential for cell and organism development and homeostasis and is orchestrated through a specialised endosomal nanodomain, the retrieval sub-domain. Sub-domain dysfunction is associated with human disease, but our mechanistic...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Carlos Antón-Plágaro, Kai-en Chen, Qian Guo, Meihan Liu, Ashley J. Evans, Philip A. Lewis, Kate J. Heesom, Kevin A. Wilkinson, Brett M. Collins, Peter J. Cullen
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Online Access:	https://doi.org/10.1038/s41467-025-61802-1