CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics

Propionyl-CoA carboxylase (PCC) is a multienzyme complex consisting of up to six α-subunits and six β-subunits. Belonging to a metabolic pathway converging on the citric acid cycle, it is present in most forms of life and irregularities in its assembly lead to serious illness in humans, known as pro...

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Bibliographic Details

Published in:	Journal of Structural Biology: X
Main Authors:	Jane K.J. Lee, Yun-Tao Liu, Jason J. Hu, Inna Aphasizheva, Ruslan Aphasizhev, Z. Hong Zhou
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Subjects:	Propionyl-CoA Statistical mechanics Thermodynamics Rate constant Conformation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590152423000041