Molecular characterization of AIFM2/FSP1 inhibition by iFSP1-like molecules

Abstract Ferroptosis is a form of cell death characterized by phospholipid peroxidation, where numerous studies have suggested that the induction of ferroptosis is a therapeutic strategy to target therapy refractory cancer entities. Ferroptosis suppressor protein 1 (FSP1), an NAD(P)H-ubiquinone redu...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Thamara Nishida Xavier da Silva, Clemens Schulte, Ariane Nunes Alves, Hans Michael Maric, José Pedro Friedmann Angeli
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-04-01
Online Access:	https://doi.org/10.1038/s41419-023-05787-z