The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma

Indoleamine 2,3 dioxygenase 1 (IDO1), a leader tryptophan-degrading enzyme, represents a recognized immune checkpoint molecule. In neoplasia, IDO1 is often highly expressed in dendritic cells infiltrating the tumor and/or in tumor cells themselves, particularly in human melanoma. In dendritic cells,...

Full description

Bibliographic Details

Published in:	OncoImmunology
Main Authors:	E Orecchini, ML Belladonna, MT Pallotta, C Volpi, L Zizi, E Panfili, M Gargaro, F Fallarino, S Rossini, C Suvieri, A Macchiarulo, S Bicciato, G Mondanelli, C Orabona
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Indoleamine 2 3-dioxygenase 1 (IDO1) immune checkpoint immunoreceptor Tyrosine-based inhibitory motif (ITIM) IDO1 signaling function B16 melanoma
Online Access:	https://www.tandfonline.com/doi/10.1080/2162402X.2023.2170095